Oxytocin enhances the experience of attachment security.
Oxytocin enhances the experience of attachment security.
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DOI：
10.1016/j.psyneuen.2009.04.002
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发表时间：
2009-10
影响因子：
3.7
通讯作者：
Guendel, Harald
中科院分区：
文献类型：
--
作者：
Buchheim, Anna;Heinrichs, Markus;George, Carol;Pokorny, Dan;Koops, Eva;Henningsen, Peter;O'Connor, Mary-Frances;Guendel, Harald
婴儿和照顾者之间的反复互动会导致安全或不安全的关系依恋模式，而不安全的依恋可能会影响个体的情绪调节和健康。鉴于催产素增强了动物和人类的社交行为，我们假设催产素也可能促进人类的依恋安全感体验。在三周的时间间隔内，26名被归类为不安全依恋模式的健康男性学生被邀请参加两次实验。在每个疗程中，采用双盲、安慰剂对照的受试者内设计，给予单剂量的催产素或安慰剂。在这两种情况下，受试者都完成了一项基于成人依恋投射系统(AAP)的依恋任务。32个AAP图片系统介绍描述了与依恋相关的事件(例如，疾病、孤独、分离、失去)，每个介绍都伴随着代表一个安全依恋类别和三个不安全依恋类别的四个典型短语。在催产素状态下，这些不安全的受试者中有相当一部分(N=18；69%)改变了他们对“安全依恋”短语的排名，倾向于更适合于AAP图片呈现，并且相同的受试者对“不安全依恋”短语的总体评分下降。特别是，从安慰剂到催产素的情况下，对带有不安全全神贯注短语的照片进行排序的受试者数量显著减少。我们发现，单剂量鼻腔给药催产素足以诱导先前被归类为不安全的成年人的依恋安全感显著增加。
Repeated interactions between infant and caregiver result in either secure or insecure relationship attachment patterns, and insecure attachment may affect individual emotion-regulation and health. Given that oxytocin enhances social approach behavior in animals and humans, we hypothesized that oxytocin might also promote the experience of attachment security in humans. Within a 3-week interval 26 healthy male students classified with an insecure attachment pattern were invited twice to an experimental session. Within each session, a single dose of oxytocin or placebo was administered, using a double-blind, placebo-controlled within-subject design. In both conditions, subjects completed an attachment task based on the Adult Attachment Projective Picture System (AAP). Thirty-two AAP picture system presentations depicted attachment-related events (e.g. illness, solitude, separation, loss), and were each accompanied by four prototypical phrases representing one secure and three insecure attachment categories. In the oxytocin condition, a significant proportion of these insecure subjects (N = 18; 69%) changed their rankings of “secure attachment” phrases towards the more appropriate for the AAP picture presentation, and the same subjects decreased in overall rating of the “insecure attachment” phrases. In particular, there was a significant decrease in the number of subjects ranking the pictures with “insecure-preoccupied” phrases from the placebo to the oxytocin condition. We find that a single dose of intranasally administered oxytocin is sufficient to induce a significant increase in the experience of attachment security in adults classified previously as insecure.
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影响因子：
3.7
作者：
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通讯作者：
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