Pubertal development: correspondence between hormonal and physical development.
Pubertal development: correspondence between hormonal and physical development.
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DOI：
10.1111/j.1467-8624.2009.01263.x
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发表时间：
2009-03
影响因子：
4.6
通讯作者：
Pollak SD
中科院分区：
文献类型：
--
作者：
Shirtcliff EA;Dahl RE;Pollak SD
青春期标志着青春期的到来，在青少年必须面对的许多变化和调整中发挥着重要作用。性激素可以促进青春期的成熟，但目前尚不清楚如何最好地衡量青春期以及现有的测量方法如何准确地捕捉激素水平。我们比较了多个青春期指标，以确定它们之间的相互关系，包括青春期发育量表 (PDS)、青春期图片访谈 (PBIP) 和体检。我们还研究了青春期身体指标与促进青春期发育的基础激素之间的关系。参与者包括 160 名 9-14 岁的青少年（82 名男孩，78 名女孩）。基础激素是通过分层线性模型从男女睾酮和脱氢表雄酮 (DHEA) 的 32 份重复唾液样本以及女孩雌二醇的 5 份重复测量中得出的。这两项自我报告指标与考试以及彼此之间具有一定程度的一致性，大约一半的青少年的自我报告与体检处于同一阶段。不同的青春期指数彼此高度相关，这表明当不需要精确一致时，自我报告可能就足够了。然而，身体发育程度明显高于或低于同龄同龄人的青少年最有可能自我报告与体检不同的阶段。体检阶段与男孩和女孩的睾酮和 DHEA 相关性良好，而与女孩的雌二醇相关性较差。除少数例外，PDS 和 PBIP 通常与考试同时进行的基础激素相关。青春期发育的多种衡量标准都是可行的选择，每种衡量标准都有各自的优势。
Puberty marks the advent of adolescence and plays an important role in many changes and adjustments that adolescents must face. Pubertal maturation is advanced by sex hormones, yet it is not clear how best to measure puberty and how well existing measures capture hormone levels. We compared multiple indices of puberty to determine their interrelationships, including the Pubertal Development Scale (PDS), a picture-based interview about puberty (PBIP) and a physical exam. We also examined how physical pubertal measures were associated with basal hormones responsible for advancing pubertal development. Participants included 160 early adolescents (82 boys, 78 girls), 9-14 years of age. Basal hormones were derived using hierarchical linear modeling from 32 repeated saliva samples of testosterone and dehydroepiandrosterone (DHEA) in both sexes and 5 repeated measures of estradiol in girls. The two self-report measures were moderately concordant with the exam and with each other, with approximately half of the adolescents self-reporting the same stage as the physical exam. The different indices of puberty were highly correlated with each other, suggesting that self-report may be adequate when precise agreement is not necessary. Nevertheless, adolescents who were substantially more or less physically developed than their same-aged peers were most likely to self-report a stage that was different from the physical exam. The physical exam stages correlated well with boys' and girls' testosterone and DHEA, and less so with girls' estradiol. With a few exceptions, the PDS and PBIP were generally related to basal hormones in parallel with the exam. Multiple measures of pubertal development are viable options, each with respective strengths.
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影响因子：
5.1
作者：
Lucky, AW;Biro, FM;Sorg, NW
通讯作者：
Sorg, NW
影响因子：
2.9
作者：
Maskarinec, G;Morimoto, Y;Franke, AA
通讯作者：
Franke, AA
DOI：
10.1196/annals.1308.032
发表时间：
2004-01-01
期刊：
ADOLESCENT BRAIN DEVELOPMENT: VULNERABILITIES AND OPPORTUNITIES
影响因子：
--
作者：
Carskadon, MA;Acebo, C;Jenni, OG
通讯作者：
Jenni, OG
影响因子：
2.5
作者：
Fernández-Garcia, B;Lucía, A;Terrados, N
通讯作者：
Terrados, N
影响因子：
3.3
作者：
Granger, DA;Shirtcliff, EA;Hastings, P
通讯作者：
Hastings, P