Low muscle strength and increased arterial stiffness go hand in hand.
Low muscle strength and increased arterial stiffness go hand in hand.
复制标题
低肌肉力量和增加的动脉僵硬齐头并进。
DOI：
10.1038/s41598-021-81084-z
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发表时间：
2021-02-03
影响因子：
4.6
通讯作者：
Demuth I
中科院分区：
文献类型：
--
作者：
König M;Buchmann N;Seeland U;Spira D;Steinhagen-Thiessen E;Demuth I
Low handgrip strength and increased arterial stiffness are both associated with poor health outcomes, but evidence on the relationship between handgrip strength and arterial stiffness is limited. In this cross-sectional analysis of combined baseline datasets from the LipidCardio and Berlin Aging Study II cohorts we aimed to examine whether handgrip strength (HGS) is associated with arterial stiffness. 1511 participants with a median age of 68.56 (IQR 63.13–73.08) years were included. Arterial stiffness was assessed by aortal pulse wave velocity (PWV) with the Mobil-O-Graph device. Handgrip strength was assessed with a handheld dynamometer. The mean HGS was 39.05 ± 9.07 kg in men and 26.20 ± 7.47 kg in women. According to multivariable linear regression analysis per 5 kg decrease in handgrip strength there was a mean increase in PWV of 0.08 m/s after adjustment for the confounders age, sex, coronary artery disease, systolic blood pressure, body mass index, cohort, and smoking. Thus, there was evidence that low handgrip strength and increased arterial stiffness go hand in hand. Arterial stiffness can possibly create the missing link between low handgrip strength and increased cardiovascular morbidity and mortality. Causality and direction of causality remain to be determined.
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影响因子：
6.7
作者：
Koopman, Jacob J. E.;van Bodegom, David;Westendorp, Rudi G. J.
通讯作者：
Westendorp, Rudi G. J.
影响因子：
3.3
作者：
Groen, Bart B. L.;Hamer, Henrike M.;van Loon, Luc J. C.
通讯作者：
van Loon, Luc J. C.
影响因子：
4
作者：
Jackson, SHD;Weale, MR;Weale, RA
通讯作者：
Weale, RA
影响因子：
3.3
作者：
Howard, Caitlin;Ferrucci, Luigi;Semba, Richard D.
通讯作者：
Semba, Richard D.
影响因子：
4
作者：
Dalle S;Rossmeislova L;Koppo K
通讯作者：
Koppo K