History of chronic alcohol abuse is associated with increased nighttime hypoxemia in older men.
History of chronic alcohol abuse is associated with increased nighttime hypoxemia in older men.
复制标题
长期酗酒史与老年男性夜间低氧血症增加有关。
DOI：
10.1111/j.1530-0277.1987.tb01326.x
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Koerker,RM
中科院分区：
文献类型：
--
作者：
Vitiello,MV;Prinz,PN;Personius,JP;Nuccio,MA;Ries,RK;Koerker,RM
记录了19例老年戒酒男性酗酒者和19例健康对照者的夜间血氧饱和度（SaO2）。与对照组相比，酒精组夜间平均氧饱和度和最低氧饱和度显著降低，绝对（平均-最低）sao2去饱和度显著增加，且去饱和度明显高于90%。此外，酒精组有更多的个体夜间sao2平均值低于95%，夜间sao2最小值低于90%。最后，在酒精组中，发现酒精史与夜间平均和最低sao2和绝对sao2去饱和度显著相关。这项初步研究发现证据表明，长期酒精滥用可能使个体易患夜间低氧血症，进而导致睡眠呼吸暂停。然而，这种影响是温和的，需要在更大规模、更仔细控制的研究中得到证实。
The all‐night blood oxygen saturations (SaO2) of 19 older abstaining male alcoholics and 19 healthy age‐matched controls were recorded. The alcohol group had significantly lower nighttime mean and minimum oxygen saturations, significantly greater absolute (mean‐minimum) SaO2desaturations, and significantly more desaturations below 90% compared with the control group. Additionally, the alcohol group had significantly more individuals with nighttime SaO2means below 95% and nighttime SaO2minimums below 90%. Finally, within the alcohol group, alcohol history was found to significantly correlate with nighttime mean and minimum SaO2and absolute SaO2desaturation. This preliminary study finds evidence that chronic alcohol abuse may predispose an individual to nighttime hypoxemia, and, inferentially, to sleep apnea. However, the effect is modest and it will need to be confirmed in larger, more carefully controlled studies.
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DOI：
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