Sleep apnea: relationship to age, sex, and Alzheimer's dementia.
Sleep apnea: relationship to age, sex, and Alzheimer's dementia.
复制标题
睡眠呼吸暂停:与年龄、性别和阿尔茨海默氏痴呆的关系。
作者:
Smallwood,RG;Vitiello,MV;Giblin,EC;Prinz,PN
The relationship of sleep apnea to age, sex, and Alzheimer's dementia was investigated in 45 elderly subjects and 10 young males, all nonobese, normotensive, nonsmoking, with no sleep complaints and no medical problems other than Alzheimer's disease. Mean apnea Jhypopnea index [(AH)I] was significantly greater in elderly males than in young males or elderly females. Mean (AH)I and percentage of subjects with an (AH)I > 5 in the Alzheimer groups were not significantly different from age and sex-matched controls. Results were similar when the apnea index was substituted for (AH)I. The data from this preliminary study indicate that healthy, elderly males with no sleep complaints and elderly males with Alzheimer's disease experience a significant, subclinical ventilatory impairment during sleep. Data from the 10 elderly females and 10 young males indicated no such impairment. The physiological significance of this degree of sleep apnea in otherwise healthy elderly males is unclear at present.
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DOI:
--
发表时间:
2009
期刊:
Acta medica Scandinavica. Supplementum
影响因子:
--
作者:
R. Ylikahri;M. Kähönen;I. Hassinen
通讯作者:
I. Hassinen
影响因子:
6.5
作者:
J. L. Swanson;D. Wayte;E. B. Helwig
通讯作者:
E. B. Helwig
DOI:
--
发表时间:
1976
期刊:
Cleveland Clinic quarterly
影响因子:
--
作者:
J. Krebs;H. Roenigk;S. Deodhar;B. Barna
通讯作者:
B. Barna
影响因子:
10.3
作者:
C. Bennett;P. Copeman
通讯作者:
P. Copeman
影响因子:
6.2
作者:
H. Trau;D. Rigel;M. Harris;A. Kopf;R. Friedman;S. Gumport;R. Bart;W. Robson N. Grier
通讯作者:
W. Robson N. Grier