Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi.
Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi.
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DOI：
10.1038/srep01425
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发表时间：
2013
影响因子：
4.6
通讯作者：
Broadley, Martin R.
中科院分区：
文献类型：
--
作者：
Hurst, Rachel;Siyame, Edwin W. P.;Young, Scott D.;Chilimba, Allan D. C.;Joy, Edward J. M.;Black, Colin R.;Ander, E. Louise;Watts, Michael J.;Chilima, Benson;Gondwe, Jellita;Kang'ombe, Dalitso;Stein, Alexander J.;Fairweather-Tait, Susan J.;Gibson, Rosalind S.;Kalimbira, Alexander A.;Broadley, Martin R.
硒（Se）是人体必需的微量营养素，在免疫功能和抗氧化防御中具有关键作用。估计膳食硒摄入量和状态是稀缺的非洲，虽然作物调查表明，缺乏可能是普遍存在的马拉维。在这里，我们表明，硒缺乏症可能是地方性的，在马拉维的基础上，成年人食用的食物从对比土壤类型的硒状态。这些数据与食物平衡表和成分表相一致，表明>80%的马拉维人口面临膳食硒不足的风险。在南部非洲的其他七个国家，膳食硒不足的风险超过60%，整个非洲为22%。鉴于大多数马拉维的土壤不能提供足够的硒作物足够的人类营养，干预措施，以减轻硒缺乏症的成本和效益应确定，例如，硒丰富的氮肥可以采用在芬兰。
Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely endemic in Malawi based on the Se status of adults consuming food from contrasting soil types. These data are consistent with food balance sheets and composition tables revealing that >80% of the Malawi population is at risk of dietary Se inadequacy. Risk of dietary Se inadequacy is >60% in seven other countries in Southern Africa, and 22% across Africa as a whole. Given that most Malawi soils cannot supply sufficient Se to crops for adequate human nutrition, the cost and benefits of interventions to alleviate Se deficiency should be determined; for example, Se-enriched nitrogen fertilisers could be adopted as in Finland.
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