Recollection, familiarity, and cortical reinstatement: a multivoxel pattern analysis.
Recollection, familiarity, and cortical reinstatement: a multivoxel pattern analysis.
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DOI：
10.1016/j.neuron.2009.08.011
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发表时间：
2009-09-10
期刊：
影响因子：
16.2
通讯作者：
Norman, Kenneth A.
中科院分区：
文献类型：
--
作者：
Johnson, Jeffrey D.;McDuff, Susan G. R.;Rugg, Michael D.;Norman, Kenneth A.
外显记忆的检索被认为涉及到对某一情节进行编码时的神经认知过程的恢复。之前的 fMRI 研究和计算模型表明，恢复仅限于回忆特定情节细节的情况。我们利用对 fMRI 数据的多象素模式分类分析来研究恢复与不同记忆判断的关联，尤其是那些伴随着回忆的判断与熟悉感（当回忆缺失时）的判断。对分类器进行了训练，以区分与不同编码任务相关的大脑活动模式，随后将其应用于与识别相关的 fMRI 数据，以确定模式的恢复程度。在基于回忆和熟悉程度的判断中，恢复都很明显，这清楚地证明了恢复不足以引起回忆性体验。这些发现被解释为支持一种持续的、与回忆相关的神经信号，而这种信号正是最近关于识别记忆过程本质的争论的核心。
Episodic memory retrieval is thought to involve reinstatement of the neurocognitive processes engaged when an episode was encoded. Prior fMRI studies and computational models have suggested that reinstatement is limited to instances in which specific episodic details are recollected. We used multi-voxel pattern-classification analyses of fMRI data to investigate how reinstatement is associated with different memory judgments, particularly those accompanied by recollection versus a feeling of familiarity (when recollection is absent). Classifiers were trained to distinguish between brain activity patterns associated with different encoding tasks, and were subsequently applied to recognition-related fMRI data to determine the degree to which patterns were reinstated. Reinstatement was evident during both recollection- and familiarity-based judgments, providing clear evidence that reinstatement is not sufficient for eliciting a recollective experience. The findings are interpreted as support for a continuous, recollection-related neural signal that has been central to recent debate over the nature of recognition memory processes.
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