Low birth weight is associated with components of the metabolic syndrome.
Low birth weight is associated with components of the metabolic syndrome.
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DOI：
10.1016/j.metabol.2009.12.001
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发表时间：
2010-09
影响因子：
9.8
通讯作者：
Yi, Zeng
中科院分区：
文献类型：
--
作者：
Xiao, Xinhua;Zhang, Zhen-Xin;Li, Wen-Hui;Feng, Kai;Sun, Qi;Cohen, Harvey Jay;Xu, Tao;Wang, Heng;Liu, Ai-Min;Gong, Xiao-Ming;Shen, Ying;Yi, Zeng
[目的]探讨中国城市人群出生体重与代谢综合征(METS)组分数量的关系。2,019名出生于1921年至1954年北京协和医院(PUMCH)并有详细产科记录的个人，自愿参加，并于2003年5月至2005年4月期间在临床环境中接受医务人员的检查。采用单因素方差分析和多元有序回归分析成年后出生结局和临床检查结果，以估计出生体重与METS的关系。METS的定义是根据国家胆固醇教育计划(NCEP)成人治疗小组(ATPIII)。METS的患病率为26.74%，但55.43%的受试者至少有两种METS。在随访中，服用全部五种蛋氨酸的受试者出生体重明显较低，年龄、BMI和腰围较高。多因素有序回归分析显示，与出生体重在3,000-3,500g之间的受试者相比，出生体重在+1；2500g的受试者成年后患上更多数量的蛋氨酸的可能性增加了66%(95%CI：1.18-2.34，p=0.004)，而出生体重在2,500-3,000g之间的受试者成年后患上更多的蛋氨酸成分的可能性增加了33%(95%CI：1.09-1.63，p=0.005)。本研究证实了中国成人低出生体重与蛋氨酸含量增加之间的关系。
To investigate the association between birth weight and number of metabolic syndrome (MetS) components in an urban Chinese cohort. Individuals (n=2,019), who were born between 1921 and 1954 at the Peking Union Medical College Hospital (PUMCH) and who had detailed obstetric records, volunteered to take part and were examined by medical personnel in a clinical setting between May 2003 and April 2005. Data of birth outcome and results on clinic examination in adulthood were analyzed using ANOVA and multivariate ordinal regression to estimate the association between birth weight and MetS. MetS was defined as per the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP III). The prevalence of MetS was 26.74%, though 55.43% of the subjects had at least two components of MetS. Subjects who presented with all five components of MetS exhibited a significantly lower birth weight and higher age, BMI, and waist circumference at follow-up. Multivariate ordinal regression analysis revealed that, as compared to those with birth weights of 3000-3500 g, subjects who had birth weights of < 2500 g were 66% more likely to develop a greater number of MetS components in adulthood (95%CI: 1.18-2.34, p=0.004), whereas those with birth weights between 2500-3000 g were 33% more likely to develop a greater number of MetS components as adults (95%CI: 1.09-1.63, p=0.005). The present study demonstrated the relationship between low birth weight and increased presentation of MetS components in Chinese adults.
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影响因子：
4.5
作者：
Elshibly, Eltahir M.;Schmalisch, Gerd
通讯作者：
Schmalisch, Gerd
DOI：
10.1590/s0034-89102008000100002
发表时间：
2008-02-01
期刊：
Revista de Saúde Pública
影响因子：
--
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Shaw, Jonathan E.
影响因子：
8.2
作者：
Jaquet, D;Deghmoun, S;Lévy-Marchal, C
通讯作者：
Lévy-Marchal, C
影响因子：
5.8
作者：
Gale, CR;Martyn, CN;Cooper, C
通讯作者：
Cooper, C