Flexible Transient Optical Waveguides and Surface-Wave Biosensors Constructed from Monocrystalline Silicon.
Flexible Transient Optical Waveguides and Surface-Wave Biosensors Constructed from Monocrystalline Silicon.
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DOI:
10.1002/adma.201801584
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发表时间:
2018-08
期刊:
影响因子:
--
通讯作者:
Rogers JA
中科院分区:
文献类型:
--
作者:
Bai W;Yang H;Ma Y;Chen H;Shin J;Liu Y;Yang Q;Kandela I;Liu Z;Kang SK;Wei C;Haney CR;Brikha A;Ge X;Feng X;Braun PV;Huang Y;Zhou W;Rogers JA
Optical technologies offer important capabilities in both biological research and clinical care. Recent interest is in implantable devices that provide intimate optical coupling to biological tissues for a finite time period and then undergo full bioresorption into benign products, thereby serving as temporary implants for diagnosis and/or therapy. The results presented here establish a silicon-based, bioresorbable photonic platform that relies on thin filaments of monocrystalline silicon encapsulated by polymers as flexible, transient optical waveguides for accurate light delivery and sensing at targeted sites in biological systems. Comprehensive studies of the mechanical and optical properties associated with bending and unfurling the waveguides from wafer-scale sources of materials establish general guidelines in fabrication and design. Monitoring biochemical species such as glucose and tracking physiological parameters such as oxygen saturation using near-infrared spectroscopic methods demonstrate modes of utility in biomedicine. These concepts provide versatile capabilities in biomedical diagnosis, therapy, deep-tissue imaging and surgery, and suggest a broad range of opportunities for silicon photonics in bioresorbable technologies.
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影响因子:
16.6
作者:
Nizamoglu S;Gather MC;Humar M;Choi M;Kim S;Kim KS;Hahn SK;Scarcelli G;Randolph M;Redmond RW;Yun SH
通讯作者:
Yun SH
影响因子:
5
作者:
Makadia HK;Siegel SJ
通讯作者:
Siegel SJ
影响因子:
56.9
作者:
Khang, DY;Jiang, HQ;Rogers, JA
通讯作者:
Rogers, JA
影响因子:
25
作者:
Shemesh OA;Tanese D;Zampini V;Linghu C;Piatkevich K;Ronzitti E;Papagiakoumou E;Boyden ES;Emiliani V
通讯作者:
Emiliani V
影响因子:
10.8
作者:
Hwang, Suk-Won;Lee, Chi Hwan;Rogers, John A.
通讯作者:
Rogers, John A.