The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation.

The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation.
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DOI:
10.1016/j.cell.2021.02.028
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发表时间:
2021-03-18
期刊:
影响因子:
64.5
通讯作者:
Tye KM
Tye KM
中科院分区:
生物学1区
文献类型:
--
作者:
Lee CR;Chen A;Tye KM

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社会稳态是个体检测社会联系的数量和质量,将其与指挥中心的既定设定点进行比较,并调整所花费的努力以寻求通过效应器系统表达的最佳社会联系的能力。当社会接触不足或过度时,社会接触分别成为积极或消极的效价刺激。慢性赤字导致设定点的适应,如重新引入到以前的最佳经验作为一个盈余。在这里,我们建立在以前的社会稳态模型,包括适应环境条件的持久变化,如长期隔离。
Social homeostasis is the ability of individuals to detect the quantity and quality of social contact, compare it to an established set-point in a command center, and adjust the effort expended to seek the optimal social contact expressed via an effector system. Social contact becomes a positive or negative valence stimulus when it is deficient or in excess, respectively. Chronic deficits lead to set-point adaptations such that reintroduction to the previous optimum is experienced as a surplus. Here, we build upon previous models for social homeostasis to include adaptations to lasting changes in environmental conditions, such as with chronic isolation.
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