Trans-acting small interfering RNA4: key to nutraceutical synthesis in grape development?
Trans-acting small interfering RNA4: key to nutraceutical synthesis in grape development?
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DOI:
10.1016/j.tplants.2013.07.006
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发表时间:
2013-11
影响因子:
20.5
通讯作者:
Rock, Christopher D.
中科院分区:
文献类型:
--
作者:
Rock, Christopher D.
The facility and versatility of microRNAs (miRNAs) to evolve and change likely underlies how they have become dominant constituents of eukaryotic genomes. In this opinion article I propose that trans-acting small interfering RNA gene 4 (TAS4) evolution may be important for biosynthesis of polyphenolics, arbuscular symbiosis, and bacterial pathogen etiologies. Expression-based and phylogenetic evidence shows that TAS4 targets two novel grape (Vitis vinifera L.) MYB transcription factors (VvMYBA6, VvMYBA7) that spawn phased siRNAs and likely function in nutraceutical bioflavonoid biosynthesis and fruit development. Characterization of the molecular mechanisms of TAS4 control of plant development and integration into biotic and abiotic stress- and nutrient signaling regulatory networks has applicability to molecular breeding and development of strategies for engineering healthier foods.
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