Toxicological effects of nanoselenium in animals.

Toxicological effects of nanoselenium in animals.
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纳米硒在动物体内的毒理学效应

DOI:
10.1186/s40104-022-00722-2
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发表时间:
2022-06-17
影响因子:
7
通讯作者:
Horky, Pavel
Horky, Pavel
中科院分区:
农林科学1区
文献类型:
--
作者:
Bano, Iqra;Skalickova, Sylvie;Arbab, Safia;Urbankova, Lenka;Horky, Pavel

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畜牧生产系统的生产力和可持续性受动物营养的严重影响。为了在动物生命的不同阶段维持体内的内稳态平衡,必须优化家畜饲料中有机活性矿物质的百分比。硒(Se)是一种关键的微量矿物质,对维持身体的许多功能是必需的。十年前,由于其非凡的特性,硒纳米粒子(SeNPs)在各种应用中引起了研究人员的极大兴趣。与较大尺寸的材料相比,SeNPs具有显著优势,它具有相对更宽的表面积、更高的表面能和较大的体积。尽管SeNPs有好处,但它也有毒性作用,因此为了成功应用必须考虑安全问题。SeNPs对动物的毒理学效应表现为体重减轻和死亡率增加。一种确保动物、人类和环境安全的策略将有助于早期诊断与SeNPs相关的所有风险。这篇综述旨在描述SeNPs在各种动物中的有益用途和潜在毒性。它还将总结为了使动物有更好的生产性能应在家畜饲料中添加的不同水平的SeNPs。
The productivity and sustainability of livestock production systems are heavily influenced by animal nutrition. To maintain homeostatic balance in the body of the animal at different phases of life, the percentage of organically active minerals in livestock feed must be optimized. Selenium (Se) is a crucial trace mineral that is required for the maintenance of many functions of the body. Se nanoparticles (SeNPs) attracted considerable interest from researchers for a variety of applications a decade ago, owing to their extraordinary properties. SeNPs offer significant advantages over larger-sized materials, by having a comparatively wider surface area, increased surface energy, and high volume. Despite its benefits, SeNP also has toxic effects, therefore safety concerns must be taken for a successful application. The toxicological effects of SeNPs in animals are characterized by weight loss, and increased mortality rate. A safe-by-strategy to certify animal, human and environmental safety will contribute to an early diagnosis of all risks associated with SeNPs. This review is aimed at describing the beneficial uses and potential toxicity of SeNPs in various animals. It will also serve as a summary of different levels of SeNPs which should be added in the feed of animals for better performance.
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