Characterization of a high-resolution hybrid DOI detector for a dedicated breast PET/CT scanner.
Characterization of a high-resolution hybrid DOI detector for a dedicated breast PET/CT scanner.
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DOI：
10.1088/0031-9155/57/11/3435
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发表时间：
2012-06-07
影响因子：
3.5
通讯作者：
Badawi RD
中科院分区：
文献类型：
--
作者：
Godinez F;Chaudhari AJ;Yang Y;Farrell R;Badawi RD
本研究的目的是设计和测试一种用于专用乳腺PET/CT扫描仪的新型高分辨率混合相互作用深度（DOI）检测器。已经设计并建造了两个探测器。完成的探测器基于1.5×1.5×20毫米未抛光的正硅酸镥（LSO）闪烁晶体14×14阵列，每个元素都涂有50 μm的反射材料层。探测器两端使用位置敏感光电倍增管（PSPMT）和大有源面积（20 × 20 mm2）雪崩光电二极管（APD）进行读出，以获取DOI信息。利用核仪器模块对探测器的时序、内禀空间分辨率（ISR）、能量分辨率以及DOI分辨率（双端读出配置）进行了表征。APD测量在10°C的温度下进行。所有的晶体在所有的深度都被识别出来，即使PSPMT的信号振幅随着距离它的深度而减小。我们测量的时序分辨率为2.4 ns，平均能量分辨率为19%。测量的平均ISR为1.2毫米的晶体在面对面位置的探测器阵列的中心排。测量了26°和51°斜入射光子对应的两个偏离中心位置，这两个位置的平均ISR分别为1.5 mm和1.7 mm。测量到所有晶体和深度的平均DOI分辨率为2.9毫米（包括0.6毫米的光束宽度）。该检测器设计显示出作为专用乳腺PET/CT扫描仪的高分辨率检测器的良好前景。
The aim of this study is to design and test a new high resolution hybrid depth of interaction (DOI) detector for a dedicated breast PET/CT scanner. Two detectors have been designed and built. The completed detectors are based on a 14×14 array of 1.5×1.5×20 mm3unpolished lutetium orthosilicate (LSO) scintillation crystals, with each element coated in a 50 μm layer of reflective material. The detector is read out from both ends using a position sensitive photomultiplier tube (PSPMT) and a large active area (20 × 20 mm2) avalanche photodiode (APD) to enable acquisition of DOI information. Nuclear instrumentation modules were used to characterize the detectors’ performances in terms of timing, intrinsic spatial resolution (ISR) and energy resolution, as well as DOI resolution with a dual ended readout configuration. Measurements with the APD were performed at a temperature of 10°C. All crystals were identified at all depths, even though the signal amplitude from the PSPMT decreases with depth away from it. We measured a timing resolution of 2.4 ns, and an average energy resolution of 19%. The mean ISR was measured to be 1.2 mm for crystals in the central row of the array for detectors in the face-to-face position. Two off-center positions were measured corresponding to 26° and 51° oblique photon incidence, and the mean ISR at these positions was 1.5 mm and 1.7 mm, respectively. The average DOI resolution across all crystals and depths was measured to be 2.9 mm (including the beam width of 0.6 mm). This detector design shows good promise as a high resolution detector for a dedicated breast PET/CT scanner.
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DOI：
10.1111/j.1754-9485.2010.02230.x
发表时间：
2011-02
影响因子：
1.6
作者：
Raylman RR;Abraham J;Hazard H;Koren C;Filburn S;Schreiman JS;Kurian S;Majewski S;Marano GD
通讯作者：
Marano GD
影响因子：
1.8
作者：
Chaudhari, Abhijit J.;Yang, Yongfeng;Badawi, Ramsey D.
通讯作者：
Badawi, Ramsey D.
影响因子：
1.8
作者：
MOSES, WW;DERENZO, SE;MANENTE, RA
通讯作者：
MANENTE, RA
影响因子：
19.7
作者：
Rosen, EL;Turkington, TG;Coleman, RE
通讯作者：
Coleman, RE
影响因子：
3.5
作者：
Chaudhari AJ;Joshi AA;Bowen SL;Leahy RM;Cherry SR;Badawi RD
通讯作者：
Badawi RD