Avian influenza and poultry workers, Peru, 2006.
Avian influenza and poultry workers, Peru, 2006.
复制标题
DOI：
10.1111/j.1750-2659.2007.00009.x
复制
发表时间：
2007-03
影响因子：
4.4
通讯作者：
Gray GC
中科院分区：
文献类型：
--
作者：
Ortiz EJ;Kochel TJ;Capuano AW;Setterquist SF;Gray GC
背景目前，亚洲、非洲和欧洲的许多国家都面临着家禽和人类感染高致病性禽流感（AI）的情况。 在世界上最大的家禽出口国美洲，正在制定和评估应急计划，为这些病毒株的到来做准备。 通过这项横断面研究，据我们所知，这是中美洲或南美洲的第一项此类研究，我们试图了解秘鲁家禽工人是否有既往感染AI的证据，如果有，确定感染的风险因素。 方法我们对秘鲁家禽养殖场的149名工人（132名接触家禽和17名未接触对照）进行了横断面血清阳性率研究，使用血凝抑制（HI）试验检测血清样本中的人流感病毒暴露。 对所有血清样品进行中和试验，以检测针对原型AI菌株H4至H12的抗体。 结果使用多变量比例优势模型，我们发现两组（暴露组和非暴露组）中抗AI病毒滴度升高的患病率均较低。 结论在南美洲进行的第一次横断面研究中，没有发现秘鲁家禽工人既往感染禽流感的证据。 这是拉丁美洲第一次对AI进行职业研究，令人鼓舞，但它可能反映了具有较高生物安全性的家禽生产部门。
Background Currently numerous countries in Asia, Africa and Europe are encountering highly pathogenic avian influenza (AI) infections in poultry and humans. In the Americas, home of the world’s largest poultry exporters, contingency plans are being developed and evaluated in preparation for the arrival of these viral strains. Objectives With this cross‐sectional study, to our knowledge the first in its kind in Central or South America, we sought to learn whether Peruvian poultry workers had evidence of previous AI infection and if so, to determine the risk factors for infection. Methods We performed a cross‐sectional seroprevalence study among 149 workers on a Peruvian poultry farm (132 exposed to poultry and 17 non‐exposed controls), serum samples were tested for human influenza virus exposure using a hemagglutination inhibition (HI) assay. Microneutralization assays were performed on all serum samples to detect antibodies against prototypic AI strains H4 through H12. Results Using multivariate proportional odds modeling we found that the prevalence of elevated titers against AI viruses was low in both groups, exposed and non‐exposed controls. Conclusions No evidence of previous AI infection among Peruvian poultry workers was found in this first cross‐sectional study performed in South America. This first occupational study of AI in Latin America was encouraging, but it likely reflects the sector of poultry production with higher biosecurity.
登录
查看更多内容
DOI：
10.1590/s0102-09352001000300005
发表时间：
2001-06-01
影响因子：
0.4
作者：
Oliveira, JG;Belluci, MSP;Loureiro, BO
通讯作者：
Loureiro, BO
影响因子：
6.4
作者：
Bridges, CB;Lim, W;Katz, JM
通讯作者：
Katz, JM
影响因子：
6.4
作者：
Mounts, AW;Kwong, H;Fukuda, K
通讯作者：
Fukuda, K
影响因子：
11.8
作者：
Suarez DL;Senne DA;Banks J;Brown IH;Essen SC;Lee CW;Manvell RJ;Mathieu-Benson C;Moreno V;Pedersen JC;Panigrahy B;Rojas H;Spackman E;Alexander DJ
通讯作者：
Alexander DJ
影响因子：
9.4
作者：
Rowe, T;Abernathy, RA;Katz, JM
通讯作者：
Katz, JM