Measurable Range of Subfoveal Choroidal Thickness With Conventional Spectral Domain Optical Coherence Tomography.
Measurable Range of Subfoveal Choroidal Thickness With Conventional Spectral Domain Optical Coherence Tomography.
复制标题
DOI：
10.1167/tvst.7.5.16
复制
发表时间：
2018-09
影响因子：
3
通讯作者：
Ham DI
中科院分区：
文献类型：
--
作者：
Kong M;Choi DY;Han G;Song YM;Park SY;Sung J;Hwang S;Ham DI
本文研究了常规光谱域光学相干断层扫描（SD-OCT）对正常健康眼睛中央凹下脉络膜厚度（SFCT）的测量范围。所有受试者均采用标准和增强深度成像（EDI）技术进行以中央凹为中心的SD-OCT水平线扫描。如果确定了两个脉络膜边界，则两个独立观察者手动测量标准图像和EDI-OCT图像上的SFCT。评价标准OCT测量成功率。采用类间、类内相关系数和Bland-Altman图进行分析。对374名受试者724只正常健康眼睛的OCT图像进行了评价。虽然在所有OCT图像上都能识别出内脉络膜边界，但在724张常规OCT图像中，有378张（52.2%）能识别出外脉络膜边界。EDI-OCT图像测量的所有研究眼的平均SFCT为292.6±94.0。在SFCT <241、241 ~ 280、281 ~ 320、321 ~ 360和bb0 ~ 360 μm范围内，常规OCT的测量成功率分别为100%、87.5%、48.1%、33.0%和0%。在SFCT≤240 μm、≤280 μm和≤320 μm范围内，常规OCT累计测量成功率分别为100%、96.4%和82.2%。两种方案显示出良好的SFCT相互相关性，在两次扫描中均可测量SFCT。常规OCT可在脉络膜较薄的眼内测量SFCT，其测量值与EDI-OCT测量值吻合度较高。在这样的眼睛中，常规OCT可以潜在地用于评估视网膜和脉络膜。在具有薄脉络膜的眼睛中，常规OCT可以潜在地用于评估视网膜和脉络膜，与EDI-OCT高度一致。
We investigate the measurable range of subfoveal choroidal thickness (SFCT) with conventional spectral domain optical coherence tomography (SD-OCT) in normal healthy eyes. All subjects underwent an SD-OCT horizontal line scan centered at the fovea with standard and enhanced depth imaging (EDI) techniques. Two independent observers manually measured SFCT on standard and EDI-OCT images, if two choroidal borders were identified. The rate of successful measurement with standard OCT was evaluated. Inter- and intraclass correlation coefficients and Bland-Altman plots were used for analysis. OCT images of 724 normal healthy eyes from 374 subjects were evaluated. Although the inner choroidal border was identified on all OCT images, the outer choroidal border was identified on 378 of 724 (52.2%) conventional OCT images. Mean SFCT of all study eyes measured by EDI-OCT images was 292.6 ± 94.0. The number of successful measurements with conventional OCT was 100%, 87.5%, 48.1%, 33.0%, and 0%, in the SFCT ranges of <241, 241–280, 281–320, 321–360, and >360 μm, respectively. The accumulated rate of successful measurement with conventional OCT was 100%, 96.4%, and 82.2% in the SFCT ranges of ≤240, ≤280, and ≤320 μm, respectively. Two protocols showed good inter-correlation of SFCT, when SFCT were measurable in both scans. SFCT can be measured by conventional OCT in eyes with thin choroid, and the measured value shows high agreement with those measured by EDI-OCT. In such eyes, conventional OCT can be used potentially to evaluate the retina and choroid. In eyes with a thin choroid, conventional OCT can be used potentially to evaluate the retina and choroid with high agreement with EDI-OCT.
登录
查看更多内容
影响因子：
4.2
作者：
Spaide, Richard F.;Koizumi, Hideki;Pozonni, Maria C.
通讯作者：
Pozonni, Maria C.
影响因子：
4.4
作者：
Chhablani, Jay;Barteselli, Giulio;Freeman, William R.
通讯作者：
Freeman, William R.
影响因子：
13.7
作者：
Barteselli G;Chhablani J;El-Emam S;Wang H;Chuang J;Kozak I;Cheng L;Bartsch DU;Freeman WR
通讯作者：
Freeman WR
影响因子：
4.2
作者：
Lin, DY;Blumenkranz, MS;Grosvenor, DM
通讯作者：
Grosvenor, DM
影响因子：
4.2
作者：
Spaide, Richard F.
通讯作者：
Spaide, Richard F.