Hemodynamics of Cerebral Aneurysms.
Hemodynamics of Cerebral Aneurysms.
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DOI:
10.1146/annurev.fluid.40.111406.102126
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发表时间:
2009-01-01
影响因子:
27.7
通讯作者:
Cebral JR
中科院分区:
文献类型:
--
作者:
Sforza DM;Putman CM;Cebral JR
The initiation and progression of cerebral aneurysms are degenerative processes of the arterial wall driven by a complex interaction of biological and hemodynamic factors. Endothelial cells on the artery wall respond physiologically to blood-flow patterns. In normal conditions, these responses are associated with nonpathological tissue remodeling and adaptation. The combination of abnormal blood patterns and genetics predisposition could lead to the pathological formation of aneurysms. Here, we review recent progress on the basic mechanisms of aneurysm formation and evolution, with a focus on the role of hemodynamic patterns.
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DOI:
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影响因子:
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