Effects of dietary conjugated linoleic acid on growth performance, tissue adipocytokine levels and lipid metabolism of grass carp
Effects of dietary conjugated linoleic acid on growth performance, tissue adipocytokine levels and lipid metabolism of grass carp
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日粮共轭亚油酸对草鱼生长性能、组织脂肪细胞因子水平及脂质代谢的影响
DOI：
10.1111/anu.12815
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发表时间：
2018-08
影响因子：
3.5
通讯作者：
Gui‐Fang Dong
中科院分区：
文献类型：
--
作者：
Qi Zou;Yan‐ou Yang;Bang‐Hong Wei;Deng‐hang Yu;Lu Chen;Teng Zhou;Feng Huang;Gui‐Fang Dong
通过65 d的生长试验，研究了饲料中添加共轭亚油酸（CLA）对草鱼生长性能、组织脂肪细胞因子水平和脂质代谢的影响。7种等氮和等脂饲料配制如下：0（对照）、5（CLA 5）、10（CLA 10）、15（CLA 15）、20（CLA 20）、25（CLA 25）和30（CLA 30）g/kg CLA。结果表明，饲料中添加低至25 g/kg的CLA显著抑制草鱼的生长。CLA 15 ~ CLA 30组肝脏脂质含量显著降低。CLA 5 ~ CLA 30组肝脏中瘦素和瘦素蛋白水平显著升高。CLA 5 ~ CLA 30和CLA 10 ~ CLA 30组肝脏脂肪酸合成酶（FAS）和三酰甘油脂肪酶（TGL）的mRNA表达水平也分别显著降低。总之，添加15-20 g/kg CLA对草鱼肝脏有明显的降脂作用，但对草鱼生长无影响。此外，共轭亚油酸对草鱼的降脂作用还受到脂肪细胞因子水平和组织中脂质代谢相关基因表达的调节。
A 65-day growth trial was conducted to investigate the effects of dietary conjugated linoleic acid (CLA) on growth performance, tissue adipocytokine levels and lipid metabolism of grass carp. Seven isonitrogenous and isolipidic diets were formulated as follows: 0 (control), 5 (CLA5), 10 (CLA10), 15 (CLA15), 20 (CLA20), 25 (CLA25) and 30 (CLA30) g/kg CLA. Results showed that incorporating as low as 25 g/kg CLA in the diet significantly decreased the growth of grass carp. The liver lipid content in fish fed with CLA15 to CLA30 significantly decreased. The leptin and resistin levels in liver of fish fed with CLA5 to CLA30 diets significantly increased. The mRNA expression levels of fatty acid synthase (FAS) and triacylglycerol lipase (TGL) in liver of fish fed with CLA5 to CLA30 and CLA10 to CLA30 diets also significantly decreased, respectively. In summary, the lipid-lowering effects in grass carp liver were induced by the supplementation of 15-20 g/kg CLA, but its growth remained unaffected. Moreover, the lipid-lowering effects of CLA on grass carp could also be modulated both by adipocytokine levels and by the expression of genes involved in lipid metabolism in tissues.
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影响因子：
13.5
作者：
Ong, Kuok Teong;Mashek, Mara T.;Bu, So Young;Greenberg, Andrew S.;Mashek, Douglas G.
通讯作者：
Mashek, Douglas G.
影响因子：
10.4
作者：
R. Rosa;A. M. Andrade;N. Bandarra;M. Nunes
通讯作者：
R. Rosa;A. M. Andrade;N. Bandarra;M. Nunes
影响因子：
--
作者：
Du Zheny
通讯作者：
Du Zheny
影响因子：
64.8
作者：
Yiying Zhang;R. Proenca;M. Maffei;M. Barone;L. Leopold;J. Friedman
通讯作者：
Yiying Zhang;R. Proenca;M. Maffei;M. Barone;L. Leopold;J. Friedman
共轭亚油酸改变黑鲶鱼 (Pelteobagrus vachelli) 的生长性能、组织脂质沉积和脂肪酸组成
DOI：
10.1007/s10695-014-0007-8
发表时间：
2014-11
期刊：
Fish Physiol. Biochem.
影响因子：
--
作者：
Denghang Yu;Feng Huang;Pengcheng Li;Yanou Yang
通讯作者：
Yanou Yang