SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020-March 2021.
SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020-March 2021.
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DOI:
10.3201/eid2712.211465
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发表时间:
2021-12
影响因子:
11.8
通讯作者:
PHIRST-C Group
中科院分区:
文献类型:
--
作者:
Kleynhans J;Tempia S;Wolter N;von Gottberg A;Bhiman JN;Buys A;Moyes J;McMorrow ML;Kahn K;Gómez-Olivé FX;Tollman S;Martinson NA;Wafawanaka F;Lebina L;du Toit J;Jassat W;Neti M;Brauer M;Cohen C;PHIRST-C Group
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2 seroprevalence in South Africa every 2 months during July 2020–March 2021 in randomly selected household cohorts in 2 communities. We compared seroprevalence to reported laboratory-confirmed infections, hospitalizations, and deaths to calculate infection–case, infection–hospitalization, and infection–fatality ratios in 2 waves of infection. Post–second wave seroprevalence ranged from 18% in the rural community children <5 years of age, to 59% in urban community adults 35–59 years of age. The second wave saw a shift in age distribution of case-patients in the urban community (from persons 35–59 years of age to persons at the extremes of age), higher attack rates in the rural community, and a higher infection–fatality ratio in the urban community. Approximately 95% of SARS-CoV-2 infections were not reported to national surveillance.
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DOI:
10.1016/s2214-109x(21)00289-8
发表时间:
2021-09
期刊:
The Lancet. Global health
影响因子:
--
作者:
Jassat W;Mudara C;Ozougwu L;Tempia S;Blumberg L;Davies MA;Pillay Y;Carter T;Morewane R;Wolmarans M;von Gottberg A;Bhiman JN;Walaza S;Cohen C;DATCOV author group
通讯作者:
DATCOV author group
影响因子:
4.4
作者:
Cohen C;McMorrow ML;Martinson NA;Kahn K;Treurnicht FK;Moyes J;Mkhencele T;Hellferscee O;Lebina L;Moroe M;Motlhaoleng K;Gómez-Olivé FX;Wagner R;Tollman S;Wafawanaka F;Ngobeni S;Kleynhans J;Mathunjwa A;Buys A;Maake L;Wolter N;Carrim M;Piketh S;Language B;Mathee A;von Gottberg A;Tempia S;PHIRST group
通讯作者:
PHIRST group
DOI:
10.1016/s2214-109x(21)00026-7
发表时间:
2021-05
期刊:
The Lancet. Global health
影响因子:
--
作者:
Chen X;Chen Z;Azman AS;Deng X;Sun R;Zhao Z;Zheng N;Chen X;Lu W;Zhuang T;Yang J;Viboud C;Ajelli M;Leung DT;Yu H
通讯作者:
Yu H
影响因子:
4.6
作者:
Ssentongo P;Heilbrunn ES;Ssentongo AE;Advani S;Chinchilli VM;Nunez JJ;Du P
通讯作者:
Du P
DOI:
10.1016/s0140-6736(21)00632-2
发表时间:
2021-04-03
期刊:
Lancet (London, England)
影响因子:
--
作者:
Salyer SJ;Maeda J;Sembuche S;Kebede Y;Tshangela A;Moussif M;Ihekweazu C;Mayet N;Abate E;Ouma AO;Nkengasong J
通讯作者:
Nkengasong J