Nanoparticle-mediated photothermal effect enables a new method for quantitative biochemical analysis using a thermometer.
Nanoparticle-mediated photothermal effect enables a new method for quantitative biochemical analysis using a thermometer.
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DOI:
10.1039/c5nr09051b
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发表时间:
2016-03-14
期刊:
影响因子:
6.7
通讯作者:
Li X
中科院分区:
文献类型:
--
作者:
Fu G;Sanjay ST;Dou M;Li X
We have developed a new biomolecular quantitation method, nanoparticle-mediated photothermal bioassay, using a common thermometer as the signal reader. Using immunoassay as a proof of concept, iron oxide nanoparticles (NPs) captured in the sandwich-type assay system are transformed into a near-infrared (NIR) laser-driven photothermal agent, Prussian blue (PB) NPs, which act as a photothermal probe to convert the assay signal into heat through the photothermal effect, thus allowing sensitive biomolecular quantitation using a thermometer. This is the first report of biomolecular quantitation using a thermometer, which also serves as the first attempt to introduce the nanoparticle-mediated photothermal effect for bioassays.
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影响因子:
6.1
作者:
Dou M;Sanjay ST;Benhabib M;Xu F;Li X
通讯作者:
Li X
影响因子:
6.7
作者:
Vo-Dinh T;Fales AM;Griffin GD;Khoury CG;Liu Y;Ngo H;Norton SJ;Register JK;Wang HN;Yuan H
通讯作者:
Yuan H
影响因子:
16.6
作者:
Qu, Weisi;Liu, Yingyi;Jiang, Xingyu
通讯作者:
Jiang, Xingyu
影响因子:
6.2
作者:
Li, Weiping;Li, Meng;Yu, Jinghua
通讯作者:
Yu, Jinghua
影响因子:
7.4
作者:
Liu, Hongyun;Malhotra, Ruchika;Peczuh, Mark W.;Rusling, James F.
通讯作者:
Rusling, James F.