Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
复制标题
DOI：
10.1016/j.ijid.2021.10.048
复制
发表时间：
2022-01
期刊：
影响因子：
--
通讯作者：
Brasil P
中科院分区：
文献类型：
--
作者：
Penetra SLS;da Silva MFB;Resende P;Pina-Costa A;Santos HFP;Guaraldo L;Calvet GA;Ogrzewalska M;Arantes I;Zukeram K;de Araújo MF;Lima ABM;Lopes RS;Lira-Silva LR;Moraes IV;Wakimoto MD;Fuller TL;Gabaglia CR;Espíndola OM;Bonaldo MC;Daniel-Ribeiro CT;Whitworth J;Smith C;Nielsen-Saines K;Pauvolid-Correa A;Siqueira MM;Brasil P
我们描述了一例由 SARS-CoV-2 Gamma 变种引起的长期 COVID-19 病例，该病例发生在一名完全接种疫苗的医护人员身上，该病例是在 B.1.1.33 谱系引起的感染 387 天后发生的。通过全基因组测序确认感染，并通过恢复期血清样本中中和抗体的检测证实感染。考虑到该医护人员长期接触 SARS-CoV-2、首次感染后免疫力下降、灭活疫苗预防 COVID-19 的功效较低、Gamma 变体 (VOC) 的免疫逃逸以及 COVID 后综合症的负担，该人本来可以从额外剂量的异源疫苗中受益。
We describe a case of prolonged COVID-19 caused by the SARS-CoV-2 Gamma variant in a fully vaccinated healthcare worker, 387 days after an infection caused by lineage B.1.1.33. Infections were confirmed by whole-genome sequencing and corroborated by the detection of neutralizing antibodies in convalescent serum samples. Considering the permanent exposure of this healthcare worker to SARS-CoV-2, the waning immunity after the first infection, the low efficacy of the inactivated vaccine at preventing COVID-19, the immune escape of the Gamma variant (VOC), and the burden of post-COVID syndrome, this individual would have benefited from an additional dose of a heterologous vaccine.
登录
查看更多内容
影响因子：
12.7
作者：
Yigit, Metin;Ozkaya-Parlakay, Aslinur;Senel, Emrah
通讯作者：
Senel, Emrah
DOI：
10.1016/j.lana.2021.100025
发表时间：
2021-09
期刊：
Lancet regional health. Americas
影响因子：
--
作者：
Hitchings MDT;Ranzani OT;Torres MSS;de Oliveira SB;Almiron M;Said R;Borg R;Schulz WL;de Oliveira RD;da Silva PV;de Castro DB;Sampaio VS;de Albuquerque BC;Ramos TCA;Fraxe SHH;da Costa CF;Naveca FG;Siqueira AM;de Araújo WN;Andrews JR;Cummings DAT;Ko AI;Croda J
通讯作者：
Croda J
影响因子：
11.8
作者：
Fintelman-Rodrigues N;da Silva APD;Dos Santos MC;Saraiva FB;Ferreira MA;Gesto J;Rodrigues DAS;Vale AM;de Azevedo IG;Soares VC;Jiang H;Tan H;Tschoeke DA;Sacramento CQ;Bozza FA;Morel CM;Bozza PT;Souza TML
通讯作者：
Souza TML
影响因子：
19
作者：
Konrad, Regina;Eberle, Ute;Sing, Andreas
通讯作者：
Sing, Andreas
DOI：
10.1056/nejmoa2107715
发表时间：
2021-09-02
期刊：
The New England journal of medicine
影响因子：
--
作者：
Jara A;Undurraga EA;González C;Paredes F;Fontecilla T;Jara G;Pizarro A;Acevedo J;Leo K;Leon F;Sans C;Leighton P;Suárez P;García-Escorza H;Araos R
通讯作者：
Araos R