Oral cancer: A multicenter study.
Oral cancer: A multicenter study.
复制标题
DOI：
10.4317/medoral.21999
复制
发表时间：
2018-01-01
期刊：
影响因子：
--
通讯作者：
Aminishakib P
中科院分区：
文献类型：
--
作者：
Dhanuthai K;Rojanawatsirivej S;Thosaporn W;Kintarak S;Subarnbhesaj A;Darling M;Kryshtalskyj E;Chiang CP;Shin HI;Choi SY;Lee SS;Aminishakib P
探讨口腔癌的发病率及临床病理特征。对参与机构的活检记录进行了审查，以了解2005年至2014年诊断的口腔癌病例。收集人口统计学数据和病变部位。病变部位细分为唇、舌、口底、牙龈、牙槽粘膜、腭、颊/唇粘膜、上颌骨和下颌骨。口腔癌分为7类：上皮肿瘤、唾液腺肿瘤、血液肿瘤、骨肿瘤、间叶肿瘤、牙源性肿瘤和其他。数据采用SPSS 17.0软件进行描述性统计分析。在474，851例病例中，6，151例（1.30%）被诊断为口腔癌。患者平均年龄为58.37±15.77岁。男性共确诊4,238例（68.90%），女性共确诊1911例（31.07%）。男女比例为2.22：1。口腔癌的好发部位分别为舌、唇/颊粘膜、牙龈、腭和牙槽粘膜。最常见的三种口腔癌的发生率从高到低依次为鳞状细胞癌、非霍奇金淋巴瘤和粘液表皮样癌。虽然与其他实体相比，口腔癌的患病率并不高，但口腔癌在患者中造成显著的死亡率和发病率，特别是当在疾病的晚期发现时。这项研究突出了一些口腔癌经常遇到的解剖位置。因此，临床医生不仅要注意牙齿，而且要注意口腔粘膜，特别是在高发地区，因为早期发现癌前病变或早期癌症可以增加患者治愈的机会，大大降低死亡率和发病率。这项研究还显示了儿童和老年口腔癌患者之间以及亚洲和非亚洲口腔癌患者之间的一些差异。 关键词：口腔癌，患病率，临床病理特征，回顾性研究。
To determine the prevalence and clinicopathologic features of the oral cancer patients. Biopsy records of the participating institutions were reviewed for oral cancer cases diagnosed from 2005 to 2014. Demographic data and site of the lesions were collected. Sites of the lesion were subdivided into lip, tongue, floor of the mouth, gingiva, alveolar mucosa, palate, buccal/labial mucosa, maxilla and mandible. Oral cancer was subdivided into 7 categories: epithelial tumors, salivary gland tumors, hematologic tumors, bone tumors, mesenchymal tumors, odontogenic tumors, and others. Data were analyzed by descriptive statistics using SPSS software version 17.0. Of the 474,851 accessioned cases, 6,151 cases (1.30%) were diagnosed in the category of oral cancer. The mean age of the patients was 58.37±15.77 years. A total of 4,238 cases (68.90%) were diagnosed in males, whereas 1911 cases (31.07%) were diagnosed in females. The male-to-female ratio was 2.22:1. The sites of predilection for oral cancer were tongue, labial/buccal mucosa, gingiva, palate, and alveolar mucosa, respectively. The three most common oral cancer in the descending order of frequency were squamous cell carcinoma, non-Hodgkin lymphoma and mucoepidermoid carcinoma. Although the prevalence of oral cancer is not high compared to other entities, oral cancer pose significant mortality and morbidity in the patients, especially when discovered late in the course of the disease. This study highlights some anatomical locations where oral cancers are frequently encountered. As a result, clinicians should pay attention to not only teeth, but oral mucosa especially in the high prevalence area as well since early detection of precancerous lesions or cancers in the early stage increase the chance of patient being cured and greatly reduce the mortality and morbidity. This study also shows some differences between pediatric and elderly oral cancer patients as well as between Asian and non-Asian oral cancer patients. Key words:Oral cancer, prevalence, clinic-pathologic features, retrospective study.
登录
查看更多内容
DOI：
10.1007/bf02907731
发表时间：
2006-01-01
影响因子：
0.6
作者：
Bhattacharjee, Abhinandan;Chakraborty, A.;Purkaystha, P.
通讯作者：
Purkaystha, P.
DOI：
10.1016/j.ijom.2007.01.007
发表时间：
2007-05-01
影响因子：
2.4
作者：
Ajayi, O. F.;Adeyemo, W. L.;Arotiba, G. T.
通讯作者：
Arotiba, G. T.
影响因子：
2.2
作者：
Scully, Crispian
通讯作者：
Scully, Crispian
影响因子：
45.3
作者：
Chaturvedi, Anil K.;Engels, Eric A.;Gillison, Maura L.
通讯作者：
Gillison, Maura L.
DOI：
10.3402/ljm.v8i0.21782
发表时间：
2013-08-27
期刊：
The Libyan journal of medicine
影响因子：
--
作者：
Anis R;Gaballah K
通讯作者：
Gaballah K