Relation between QT and RR intervals during exercise testing in atrial fibrillation.
Relation between QT and RR intervals during exercise testing in atrial fibrillation.
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房颤运动测试期间 QT 和 RR 间期之间的关系。
DOI：
10.1016/0002-9149(92)90614-5
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Kadish,AH
中科院分区：
文献类型：
--
作者：
Ehlert,FA;Goldberger,JJ;Rosenthal,JE;Kadish,AH
对10例房颤患者和10例窦性心律对照受试者在一定心率范围内预测RR-QT关系的能力进行了评估。每个受试者的数据被回归到3个标准形式的QT预测公式(Bazett的平方根公式、Fridericia的立方根公式和Sarma的指数公式)中，并用前5个RR间期的加权平均进行修正。用均方残差和Akaike信息准则评价各公式的拟合优度。对于房颤，3个标准QT预测公式(Bazett 624±274、Fridericia 625±274和Sarma 611±267)和3个改良QT预测公式(Bazett 507±325、Fridericia 496±255和Sarma 495±328)之间的均方残差无差异。在所有患者中，加权平均修正使所有3个方程(p<；0.05)的均方残差显著降低。这些发现被Akaike信息标准所证实。窦性心律的适合度与以前发表的报告相似，明显好于房颤的适合度(p<；0.0001)。10例房颤患者中有9例获得了窦性心律的心电图，并用上述回归方程预测了QT间期。比较QT间期的实测值和预测值，改良Fridericia方程的相关性最好(R2=0.93)，r2值为0.86±0.07。对先前描述的QT预测公式的拟议修改考虑了先前RR间期的影响的渐进性，并且可能在临床上用于校正房颤的QT间期。
The ability to predict the RR-QT relation over a range of heart rates was evaluated in 10 patients with atrial fibrillation (AF) and in 10 control subjects in sinus rhythm. The data from each subject were fitted by regression into 3 QT prediction formulas (the square root formula of Bazett, the cube root formula of Fridericia and the exponential formula of Sarma) applied in standard form and modified with a weighted average of the preceding 5 RR intervals. The goodness-of-fit of each formula was evaluated using mean square residual and Akaike information criterion. For AF, the mean square residuals did not differ among the 3 standard QT prediction formulas (Bazett 624 ± 274, Fridericia 625 ± 274 and Sarma 611 ± 267) and among the 3 modified QT prediction formulas (Bazett 507 ± 325, Fridericia 496 ± 255 and Sarma 495 ± 328). The weighted average modification produced a significant decrease in mean square residuals for all 3 equations (p < 0.05) in all patients. These findings were confirmed by Akaike information criterion. Goodness-of-fit in sinus rhythm was similar to previously published reports, and significantly better than the fit for AF (p < 0.0001). For 9 of the 10 patients with AF, sinus rhythm electrocardiograms were obtained and the above regression equations were used to predict QT intervals. Comparing the measured and predicted QT intervals, the best correlation was produced by the modified form of the Fridericia equation (r2= 0.93); the mean r2value was 0.86 ± 0.07. The proposed modification of previously described QT prediction formulas takes into account the gradual nature of the influences of the preceding RR intervals and may be clinically useful in correcting the QT interval in AF.
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影响因子：
4.8
作者：
S. Kovacs
通讯作者：
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影响因子：
10.8
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通讯作者：
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影响因子：
2.8
作者：
LECOCQ, B;LECOCQ, V;JAILLON, P
通讯作者：
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影响因子：
4.8
作者：
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通讯作者：
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影响因子：
--
作者：
P. Taggart;R. Donaldson;J. Green;S. Joseph;H. Kelly;J. Marcomichelakis;D. Noble;J. White
通讯作者：
J. White