Environmental surveillance identifies multiple introductions of MRSA CC398 in an Equine Veterinary Hospital in the UK, 2011-2016.
Environmental surveillance identifies multiple introductions of MRSA CC398 in an Equine Veterinary Hospital in the UK, 2011-2016.
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DOI:
10.1038/s41598-017-05559-8
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发表时间:
2017-07-14
影响因子:
4.6
通讯作者:
Timofte D
中科院分区:
文献类型:
--
作者:
Bortolami A;Williams NJ;McGowan CM;Kelly PG;Archer DC;Corrò M;Pinchbeck G;Saunders CJ;Timofte D
Bacterial environmental and surgical site infection (SSI) surveillance was implemented from 2011–2016 in a UK Equine Referral Veterinary Hospital and identified 81 methicillin-resistant Staphylococcus aureus (MRSA) isolates. A cluster of MRSA SSIs occurred in early 2016 with the isolates confirmed as ST398 by multilocus sequence typing (MLST), which prompted retrospective analysis of all MRSA isolates obtained from the environment (n = 62), SSIs (n = 13) and hand plates (n = 6) in the past five years. Sixty five of these isolates were typed to CC398 and a selection of these (n = 38) were further characterised for resistance and virulence genes, SCCmec and spa typing. Overall, MRSA was identified in 62/540 (11.5%) of environmental samples, 6/81 of the hand-plates (7.4%) and 13/208 of the SSIs (6.3%). spa t011 was the most frequent (24/38) and Based Upon Repeat Pattern (BURP) analysis identified spa t011 as one of the two group founders of the main spa CC identified across the five years (spa CC011/3423). However, 3 singletons (t073, t786, t064) were also identified suggesting separate introductions into the hospital environment. This long-term MRSA surveillance study revealed multiple introductions of MRSA CC398 in a UK Equine Hospital, identifying an emerging zoonotic pathogen so far only sporadically recorded in the UK.
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影响因子:
3.7
作者:
Monecke S;Coombs G;Shore AC;Coleman DC;Akpaka P;Borg M;Chow H;Ip M;Jatzwauk L;Jonas D;Kadlec K;Kearns A;Laurent F;O'Brien FG;Pearson J;Ruppelt A;Schwarz S;Scicluna E;Slickers P;Tan HL;Weber S;Ehricht R
通讯作者:
Ehricht R
影响因子:
2.1
作者:
Hoet, Armando E.;Johnson, Amanda;Wittum, Thomas E.
通讯作者:
Wittum, Thomas E.
影响因子:
3.7
作者:
Köck R;Schaumburg F;Mellmann A;Köksal M;Jurke A;Becker K;Friedrich AW
通讯作者:
Friedrich AW
DOI:
10.2807/1560-7917.es.2015.20.37.30021
发表时间:
2015
期刊:
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子:
--
作者:
Larsen J;Petersen A;Sørum M;Stegger M;van Alphen L;Valentiner-Branth P;Knudsen LK;Larsen LS;Feingold B;Price LB;Andersen PS;Larsen AR;Skov RL
通讯作者:
Skov RL
影响因子:
3.3
作者:
Boerlin, P;Eugster, S;Schawalder, P
通讯作者:
Schawalder, P