Low-cost mobile phone microscopy with a reversed mobile phone camera lens.

Low-cost mobile phone microscopy with a reversed mobile phone camera lens.
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DOI:
10.1371/journal.pone.0095330
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Fletcher DA
Fletcher DA
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Switz NA;D'Ambrosio MV;Fletcher DA

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The increasing capabilities and ubiquity of mobile phones and their associated digital cameras offer the possibility of extending low-cost, portable diagnostic microscopy to underserved and low-resource areas. However, mobile phone microscopes created by adding magnifying optics to the phone's camera module have been unable to make use of the full image sensor due to the specialized design of the embedded camera lens, exacerbating the tradeoff between resolution and field of view inherent to optical systems. This tradeoff is acutely felt for diagnostic applications, where the speed and cost of image-based diagnosis is related to the area of the sample that can be viewed at sufficient resolution. Here we present a simple and low-cost approach to mobile phone microscopy that uses a reversed mobile phone camera lens added to an intact mobile phone to enable high quality imaging over a significantly larger field of view than standard microscopy. We demonstrate use of the reversed lens mobile phone microscope to identify red and white blood cells in blood smears and soil-transmitted helminth eggs in stool samples.
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