A survey on subtypes and clinical characteristics of 1061 patients with urticaria in the primary care institutes in Japan
A survey on subtypes and clinical characteristics of 1061 patients with urticaria in the primary care institutes in Japan
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日本初级保健机构1061例荨麻疹患者亚型及临床特征调查
DOI：
10.1111/1346-8138.16562
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发表时间：
2022
期刊：
影响因子：
3.1
通讯作者：
Hide M
中科院分区：
文献类型：
--
作者：
Saito R;Takahagi S;Nakano F;Furutani K;Mihara S;Numata T;Kameyoshi Y;Tanaka T;Shindo H;Niimi N;Iwamoto K;Hiragun T;Hiragun M;Tanaka A;Hide M
据报道，荨麻疹的流行主要发生在欧洲和北美。然而，在初级保健实践中，特别是在亚洲国家，关于其亚型和临床特征的准确信息很少。2020年10月至11月期间，研究人员招募了10名患有荨麻疹和/或血管性水肿症的患者前往日本9家初级诊所就诊，这些诊所都是经过认可的皮肤科医生和过敏专科医生。收集年龄、性别、病程、风疹控制试验(UCT)和伴发风疹亚型等资料。共有1061名患者参与。20~50岁年龄组患者数量较多，40多岁为高峰。以慢性自发性荨麻疹(CSU)最常见，其次为皮纹病、急性自发性荨麻疹(ASU)、血管水肿型和胆碱能型(CholU)，分别为66.8%、22.7%、18.9%、14.1%和5.7%。从20多岁到50多岁，CSU的发展随着年龄的增长而增加，尤其是在女性。皮纹病在40多岁时达到高峰。亚利桑那州立大学在童年和30多岁时出现双峰。胆囊炎多见于10-20多岁的男性。血管性水肿症患者多为女性，年龄在30多岁。1061名受试者中只有14名(1.3%)出现了血管性水肿，而136名(12.8%)患者出现了伴随有荨麻疹的血管性水肿。UCT显示并发CSU和其他亚型的患者与单纯CSU的患者相比，控制不佳的荨麻疹评分较低。荨麻疹倾向于在年轻到中年女性中发展。最常见的荨麻疹亚型是CSU，而在日本，胆囊炎患者的数量很多，而血管水肿的患者数量很少。
The prevalence of urticaria has been reported mostly in Europe and North America. However, precise information regarding its subtypes and clinical characteristics in primary care practice, especially in Asian countries, are scant. Patients with urticaria and/or angioedema who visited nine primary clinics of accredited dermatologists and allergologists in Japan were recruited from October to November 2020. The information of age, sex, disease duration, urticaria control test (UCT), and concomitant urticaria subtypes were collected. A total of 1061 patients participated. The number of patients was high in the 20 to 50 age groups with a peak in the 40s. The most frequent urticaria subtype was chronic spontaneous urticaria (CSU) followed by dermographism, acute spontaneous urticaria (ASU), angioedema, and cholinergic urticaria (CholU) (66.8%, 22.7%, 18.9%, 14.1% and 5.7% in all patients with urticaria). CSU development increased with age from the 20s to 50s, especially in females. Dermographism had a peak in the 40s. ASU had bimodal peaks in childhood and in the 30s. CholU was common in males in the 10–20s. Most angioedema patients were female with an increase in their 30s. Angioedema was solely present in 14 of 1061 participants (1.3%), while 136 (12.8%) had angioedema concomitant with urticaria. UCT showed poorly controlled urticaria with lower scores in patients with concomitant CSU and other subtypes than in those with CSU alone. Urticaria tends to develop in young to middle‐aged females. The most common urticaria subtype is CSU, while the number of patients with CholU is high and that of angioedema is low in Japan.
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影响因子：
12.4
作者：
Sussman G;Abuzakouk M;Bérard F;Canonica W;Oude Elberink H;Giménez-Arnau A;Grattan C;Hollis K;Hunter S;Knulst A;Lacour JP;Lynde C;Marsland A;McBride D;Maurer M;Nakonechna A;Ortiz de Frutos J;Reynolds M;Sweeney C;Tian H;Weller K;Wolin D;Balp MM
通讯作者：
Balp MM
荨麻疹和血管性水肿的临床和病因学方面
影响因子：
10.3
作者：
E. Nettis;A. Pannofino;C. D'Aprile;A. Ferrannini;A. Tursi
通讯作者：
A. Tursi
DOI：
10.1111/jdv.17724
发表时间：
2021-11-12
影响因子：
9.2
作者：
Weller, K.;Maurer, M.;Staubach, P.
通讯作者：
Staubach, P.
影响因子：
12.4
作者：
Baiardini, I;Giardini, A;Canonica, GW
通讯作者：
Canonica, GW
DOI：
10.3904/kjim.2017.203
发表时间：
2019-03
期刊：
The Korean journal of internal medicine
影响因子：
--
作者：
Seo JH;Kwon JW
通讯作者：
Kwon JW