Adolescent Behavioral Characteristics Mediate Familial Effects on Alcohol Use and Problems in College-Bound Students.
Adolescent Behavioral Characteristics Mediate Familial Effects on Alcohol Use and Problems in College-Bound Students.
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DOI：
10.1177/1178221820970925
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Palmer RH
中科院分区：
文献类型：
--
作者：
Brown AL;España RA;Benca-Bachman CE;Welsh JW;Palmer RH
研究表明，与饮酒有关的行为范围很广。因此，目前尚不清楚精神病理学的家族风险模式是否直接或间接与青春期后期的饮酒模式和问题有关，或者由行为特征（如气质、情绪）介导。我们通过传染性责任指数（TLI）研究了精神病理学家族史对大学前饮酒和问题的直接和间接影响。参与者（N = 302; 29.6%男性）提供了自我报告的数据，包括饮酒开始的年龄，过去90天的饮酒频率和问题（AUP），内化和酒精和非法物质使用的家族史，以及TLI。大约21%的参与者报告至少有一个亲戚有定期和/或有问题的酒精使用史，而非法物质使用的比例为12%，内化问题的比例为-55%。较高的TLI分数与物质使用、酒精使用和内化问题的家族史增加以及饮酒开始年龄较早相关。内化问题家族史是AUP最可靠的指标（β = 0.20 [95% CI = 0.04-0.36]，P = 0.01）。路径分析表明，个人层面的行为，包括TLI调解的影响，家族史的年龄开始和定期饮酒。内化，饮酒和非法物质使用的家族史反映了从高中到大学过渡期间与酒精开始和使用风险相关的广泛行为的普遍风险。
Studies suggest a broad spectrum of behaviors associated with drinking. Consequently, it is unclear whether patterns of familial risk for psychopathology are directly or indirectly related to patterns of alcohol use and problems in late adolescence or mediated by behavioral characteristics, such as temperament, mood. We examined direct and indirect effects of perceived family history of psychopathology on pre-collegiate alcohol use and problems via the Transmissible Liability Index (TLI). Participants (N = 302; 29.6% male) provided self-report data on age of onset of drinking, past 90-day frequency of alcohol use and problems (AUP), family history of internalizing and alcohol and illicit substance use, and TLI. Approximately 21% of participants reported having at least one relative with a history of regular and/or problematic alcohol use, compared to 12% for illicit substance use, and −55% for internalizing problems. Higher TLI scores were associated with increased family history of substance use, alcohol use, and internalizing problems, as well as earlier age of onset of drinking. Family history of internalizing problems was the most robust indicator of AUP (β = 0.20 [95% CI = 0.04-0.36], P = .01). Path analyses suggested that the individual-level behaviors that comprise TLI mediate the effects of family history on age of initiation and regular alcohol consumption. Family history of internalizing, drinking, and illicit substance use reflect generalized risk for a broad set of behaviors associated with risk for alcohol initiation and use during the transition from high school to college.
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影响因子：
2.6
作者：
Hicks, Brian M.;Schalet, Benjamin D.;Malone, Stephen M.;Iacono, William G.;McGue, Matt
通讯作者：
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通讯作者：
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作者：
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通讯作者：
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