A Retrospective Study to Compare the Use of the Mean Apnea-Hypopnea Duration and the Apnea-Hypopnea Index with Blood Oxygenation and Sleep Patterns in Patients with Obstructive Sleep Apnea Diagnosed by Polysomnography.
A Retrospective Study to Compare the Use of the Mean Apnea-Hypopnea Duration and the Apnea-Hypopnea Index with Blood Oxygenation and Sleep Patterns in Patients with Obstructive Sleep Apnea Diagnosed by Polysomnography.
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一项回顾性研究，比较多导睡眠图诊断的阻塞性睡眠呼吸暂停患者的平均呼吸暂停-低通气持续时间和呼吸暂停-低通气指数与血氧合和睡眠模式的使用
DOI：
10.12659/msm.909219
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发表时间：
2018-03-31
期刊：
影响因子：
--
通讯作者：
Wei Y
中科院分区：
文献类型：
--
作者：
Zhan X;Fang F;Wu C;Pinto JM;Wei Y
研究背景呼吸暂停低通气指数（AHI）和平均呼吸暂停低通气持续时间（MAD）是衡量阻塞性睡眠呼吸暂停（OSA）症状严重程度的指标。本研究的目的是比较使用MAD与AHI作为多导睡眠图（PSG）诊断为OSA患者的临床和人口统计学参数、血氧和睡眠参数的指标。材料/方法回顾性研究511例经多导睡眠图（PSG）确诊的OSA患者，根据美国睡眠医学学会（AASM）的指南测量AHI和MAD。根据中位持续时间并使用四分位距（IQR）将患者分为两组：MAD短的患者和MAD长的患者，因为数据不是正态分布的。记录临床和人口统计学参数。采用脉搏血氧仪测量睡眠时的血氧饱和度，记录睡眠结构，采用埃普沃思嗜睡量表（ESS）问卷测量白天嗜睡情况。结果511例OSA患者中，MAD与AHI呈弱相关（r=0.17，P<0.01），与患者年龄（r=0.08，P=0.06）、体重（r=0.014，P=0.75）、身高（r=0.06，P=0.16）无相关性。长期MAD或重度OSA患者（n=260）的血氧水平和睡眠参数明显较差。结论对于重度OSA患者，MAD是一个有用的血氧和睡眠指标。
Background The apnea-hypopnea index (AHI) and the mean apnea-hypopnea duration (MAD) are used to measure the severity of the symptoms of obstructive sleep apnea (OSA). The aim of this study was to compare the use of the MAD with the AHI as indicators of clinical and demographic parameters, blood oxygenation, and sleep parameters in patients diagnosed with OSA by polysomnography (PSG). Material/Methods A retrospective study included 511 patients with OSA diagnosed by PSG and who had the AHI and the MAD measured according to the guidelines from the American Academy of Sleep Medicine (AASM). The patients were divided into two groups: patients with a short MAD and with a long MAD, according to median duration, and using the inter-quartile range (IQR), as the data were not normally distributed. Clinical and demographic parameters were recorded. Pulse oximetry was used to measure blood oxygen saturation during sleep, sleep structure was recorded, and the Epworth Sleepiness Scale (ESS) questionnaire was used to measure daytime sleepiness. Results In all 511 patients with OSA, the MAD was significantly, but weakly, correlated with the AHI (r=0.17, P<0.01), but showed no significant associations with patient age (r=0.08, P=0.06), body weight (r=0.014, P=0.75), and height (r=0.06, P=0.16). Patients with a long MAD or severe OSA (n=260) had significantly worse blood oxygen levels and sleep parameters. Conclusions For patients with severe OSA, this study showed that the MAD was a useful indicator of blood oxygenation and sleep parameters.
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影响因子：
120.7
作者：
Van Cauter, E;Leproult, R;Plat, L
通讯作者：
Plat, L
影响因子：
158.5
作者：
YOUNG, T;PALTA, M;BADR, S
通讯作者：
BADR, S
影响因子：
39.2
作者：
Campos-Rodriguez, Francisco;Martinez-Garcia, Miguel A.;Montserrat, Josep M.
通讯作者：
Montserrat, Josep M.
影响因子：
4.4
作者：
Lo JC;Bennion KA;Chee MW
通讯作者：
Chee MW
影响因子：
158.5
作者：
Terán-Santos, J;Jiménez-Gómez, A;Cordero-Guevara, J
通讯作者：
Cordero-Guevara, J