Simplifying nickel(0) catalysis: an air-stable nickel precatalyst for the internally selective benzylation of terminal alkenes.
Simplifying nickel(0) catalysis: an air-stable nickel precatalyst for the internally selective benzylation of terminal alkenes.
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DOI：
10.1021/ja3116718
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发表时间：
2013-01-30
影响因子：
15
通讯作者：
Jamison, Timothy F.
中科院分区：
文献类型：
--
作者：
Standley, Eric A.;Jamison, Timothy F.
空气稳定的镍（II）配合物反式-（PCy2Ph）2Ni（邻甲苯基）Cl的合成和表征结合其用于Mizoroki Heck型，室温，内部选择性耦合取代的苄基氯与末端烯烃的调查。该反应采用末端烯烃作为烯基金属等价物，以高产率和在几乎所有情况下大于95：5的区域选择性提供了快速、收敛的获得取代的烯丙基苯衍生物的途径。该反应操作简单，可以在工作台上进行，无需纯化或脱气溶剂或试剂，并且在设置期间不需要排除空气或水。预催化剂的合成通过简单的程序完成，该程序采用廉价的市售试剂，不需要纯化步骤，并且以高产率进行。
The synthesis and characterization of the air-stable nickel(II) complex trans-(PCy2Ph)2Ni(o-tolyl)Cl is described in conjunction with an investigation of its use for Mizoroki Heck-type, room temperature, internally-selective coupling of substituted benzyl chlorides with terminal alkenes. This reaction, which employs a terminal alkene as an alkenylmetal equivalent, provides rapid, convergent access to substituted allylbenzene derivatives in high yield and with regioselectivity greater than 95:5 in nearly all cases. The reaction is operationally simple, can be carried out on the bench-top with no purification or degassing of solvents or reagents, and requires no exclusion of air or water during setup. Synthesis of the precatalyst is accomplished through a straightforward procedure that employs inexpensive, commercially available reagents, requires no purification steps, and proceeds in high yield.
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影响因子：
1.8
作者：
Chen, Chen;Yang, Lian-Ming
通讯作者：
Yang, Lian-Ming
DOI：
10.1080/00304949709355222
发表时间：
1997-08-01
影响因子：
1.5
作者：
Kumar, P
通讯作者：
Kumar, P
影响因子：
2.3
作者：
Eisch, JJ;Qian, Y;Singh, M
通讯作者：
Singh, M
影响因子：
15
作者：
Li, Wei;Herath, Ananda;Montgomery, John
通讯作者：
Montgomery, John
影响因子：
3.6
作者：
CABRI, W;CANDIANI, I;SANTI, R
通讯作者：
SANTI, R