Predictors of persistent ADHD: an 11-year follow-up study.

Predictors of persistent ADHD: an 11-year follow-up study.
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DOI:
10.1016/j.jpsychires.2010.06.009
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发表时间:
2011-02
影响因子:
4.8
通讯作者:
Faraone SV
Faraone SV
中科院分区:
医学2区
文献类型:
--
作者:
Biederman J;Petty CR;Clarke A;Lomedico A;Faraone SV

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尽管存在一些对ADHD儿童的随访研究,直到成年,但关于ADHD的持续和缓解模式是否可以长期预测的信息有限。本研究的主要目的是评估ADHD持续性的预测因素,在一个大样本的男孩有和没有ADHD前瞻性地随访了11年,进入青年期。受试者为患有(N=110)和未患有(N=105)ADHD的白人非西班牙裔男孩,基线评估时年龄为6至17岁(平均年龄11岁),随访评估时年龄为15至31岁(平均年龄22岁)。受试者进行了全面和盲目的结构化诊断访谈和认知,社会,学校和家庭功能的评估。在11年的随访中,78%的ADHD儿童继续完全(35%)或部分持续(亚综合征(22%),功能受损(15%)或缓解但治疗(6%))。持续性的预测因素是ADHD严重损害、精神共病和基线时暴露于母体精神病理学。这些研究结果前瞻性地证实,ADHD的长期持续性是可以从11年前确定的心理社会逆境和精神共病中预测的。
Despite the existence of several follow-up studies of children with ADHD followed up into adulthood, there is limited information on whether patterns of persistence and remission in ADHD can be predicted over the long-term. The main aim of this study was to evaluate predictors of persistence of ADHD in a large sample of boys with and without ADHD followed prospectively for 11 years into young adulthood. Subjects were Caucasian, non-Hispanic boys with (N=110) and without (N=105) ADHD who were 6 to 17 years old at the baseline assessment (mean age 11 years) and 15 to 31 years old at the follow-up assessment (mean age 22 years). Subjects were comprehensively and blindly assessed with structured diagnostic interviews and assessments of cognitive, social, school, and family functioning. At the 11-year follow-up, 78% of children with ADHD continued to have a full (35%) or a partial persistence (subsyndromal (22%), impaired functioning (15%), or remitted but treated (6%)). Predictors of persistence were severe impairment of ADHD, psychiatric comorbidity, and exposure to maternal psychopathology at baseline. These findings prospectively confirm that persistence of ADHD over the long term is predictable from psychosocial adversity and psychiatric comorbidity ascertained 11 years earlier.
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发表时间: 2009-01-01
影响因子: 10.6
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发表时间: 1990-07-01
影响因子: 13.3
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发表时间: 1996-03-01
影响因子: 13.3
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