Phylogeography of Y-chromosome haplogroup Q1a1a-M120, a paternal lineage connecting populations in Siberia and East Asia
Phylogeography of Y-chromosome haplogroup Q1a1a-M120, a paternal lineage connecting populations in Siberia and East Asia
复制标题
Y染色体单倍群Q1a1a-M120的系统发育地理学，连接西伯利亚和东亚人群的父系谱系
DOI：
10.1080/03014460.2019.1632930
复制
发表时间：
2019-04
影响因子：
1.7
通讯作者：
Wei Lan-Hai
中科院分区：
文献类型：
--
作者：
Sun Na;Ma Peng-Cheng;Yan Shi;Wen Shao-Qing;Sun Chang;Du Pan-Xin;Cheng Hui-Zhen;Deng Xiao-Hua;Wang Chuan-Chao;Wei Lan-Hai
摘要背景：以前的研究表明，人类Y染色体单倍群Q1 a1 a-M120，一个广泛存在于东亚人群中的父系谱系，起源于南西伯利亚。然而，关于这一父系血统的起源、多样化和扩张仍存在许多不确定性。目的：探讨父系Q-M120家系在东亚的起源和传播。研究对象和方法：作者产生了26个新的Y染色体序列的Q-M120男性和共分析了45个Y染色体序列的这个单倍群。对Q-M120单倍群的系统发育树进行了高度修正。此外，还对该谱系进行了全面的地理分析，包括来自欧亚大陆东部440个种群的15，007个样本。结果：揭示了该谱系与西伯利亚人群的古老联系。然而，这一父系血统在5000年至3000年前在中国西北地区经历了一次原地扩张。Q-M120高频率的古代人群参与了2000年前古代华夏人群的形成;该单倍群最终成为现代汉族人群的创始父系谱系之一。结论：本研究提供了Q1 a1 a-M120单倍群起源和扩散过程的清晰模式，以及该父系谱系在古代华夏人群和现代汉族人群形成中的作用。
Abstract Background: Previous studies have suggested that the human Y-chromosome haplogroup Q1a1a-M120, a widespread paternal lineage in East Asian populations, originated in South Siberia. However, much uncertainty remains regarding the origin, diversification, and expansion of this paternal lineage. Aim: To explore the origin and diffusion of paternal Q-M120 lineages in East Asia. Subjects and methods: The authors generated 26 new Y chromosome sequences of Q-M120 males and co-analysed 45 Y chromosome sequences of this haplogroup. A highly-revised phylogenetic tree of haplogroup Q-M120 with age estimates was reconstructed. Additionally, a comprehensive phylogeographic analysis of this lineage was performed including 15,007 samples from 440 populations in eastern Eurasia. Results: An ancient connection of this lineage with populations in Siberia was revealed. However, this paternal lineage experienced an in-situ expansion between 5000 and 3000 years ago in northwestern China. Ancient populations with high frequencies of Q-M120 were involved in the formation of ancient Huaxia populations before 2000 years ago; this haplogroup eventually became one of the founding paternal lineages of modern Han populations. Conclusion: This study provides a clear pattern of the origin and diffusion process of haplogroup Q1a1a-M120, as well as the role of this paternal lineage during the formation of ancient Huaxia populations and modern Han populations.
登录
查看更多内容
影响因子：
3.7
作者：
Di Cristofaro J;Pennarun E;Mazières S;Myres NM;Lin AA;Temori SA;Metspalu M;Metspalu E;Witzel M;King RJ;Underhill PA;Villems R;Chiaroni J
通讯作者：
Chiaroni J
大数据中心：从沉积到集成再到转换。
影响因子：
14.9
作者：
BIG Data Center Members
通讯作者：
BIG Data Center Members
影响因子：
4.6
作者：
Finocchio A;Trombetta B;Messina F;D'Atanasio E;Akar N;Loutradis A;Michalodimitrakis EI;Cruciani F;Novelletto A
通讯作者：
Novelletto A
影响因子：
7
作者：
A. Redd
通讯作者：
A. Redd
扩展的 Y 染色体研究表明现代人类通过北方路线迁徙到东亚
影响因子：
10.7
作者：
Zhong, Hua;Shi, Hong;Ma, Runlin Z.
通讯作者：
Ma, Runlin Z.