Current status of Paragonimus and paragonimiasis in Ecuador.
Current status of Paragonimus and paragonimiasis in Ecuador.
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DOI：
10.1590/0074-0276140042
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发表时间：
2014-11
影响因子：
2.8
通讯作者：
Sugiyama H
中科院分区：
文献类型：
--
作者：
Calvopiña M;Romero D;Castañeda B;Hashiguchi Y;Sugiyama H
对厄瓜多尔关于并殖吸虫病的国家和国际出版物、公共卫生部的流行病学记录和未发表的研究数据进行了审查，以总结寄生虫/疾病的现状。审查的目的是教育医生、决策者和保健提供者了解这种疾病的状况，并鼓励科学调查人员进行进一步的研究。并殖吸虫病于94年前首次在厄瓜多尔被诊断出来，目前在太平洋沿岸和亚马逊地区的24个省中的19个省的热带和亚热带地区流行。墨西哥并殖吸虫是该国唯一已知的物种，软体动物Aroapyrgus colleagensis和螃蟹Moreirocarcinus embryatus，Hypolobocera chilensis和Hypolobocera aequatorialis分别是初级和次级中间宿主。最近的研究发现，在亚马逊北方的毛趾蟹中发现了墨西哥披索氏囊蚴。慢性肺并殖吸虫病通常被误诊为结核病并作为结核病治疗，虽然研究表明吡喹酮和三氯苯达唑对治疗人类感染有效，但厄瓜多尔没有这两种药物。1978年至2007年的官方数据显示，19个省的年发病率为85.5例，估计有17.2%的人口面临感染风险。目前没有关于感染发生率/流行率的数据，也没有国家控制方案。
A review of national and international publications on paragonimiasis in Ecuador, epidemiological records from the Ministry of Public Health and unpublished research data was conducted to summarise the current status of the parasite/disease. The purpose of the review is to educate physicians, policy-makers and health providers on the status of the disease and to stimulate scientific investigators to conduct further research. Paragonimiasis was first diagnosed in Ecuador 94 years ago and it is endemic to both tropical and subtropical regions in 19 of 24 provinces in the Pacific Coast and Amazon regions. Paragonimus mexicanus is the only known species in the country, with the mollusc Aroapyrgus colombiensis and the crabs Moreirocarcinus emarginatus, Hypolobocera chilensis and Hypolobocera aequatorialis being the primary and secondary intermediate hosts, respectively. Recent studies found P. mexicanus metacercariae in Trichodactylus faxoni crabs of the northern Amazon. Chronic pulmonary paragonimiasis is commonly misdiagnosed and treated as tuberculosis and although studies have demonstrated the efficacy of praziquantel and triclabendazole for the treatment of human infections, neither drug is available in Ecuador. Official data recorded from 1978-2007 indicate an annual incidence of 85.5 cases throughout the 19 provinces, with an estimated 17.2% of the population at risk of infection. There are no current data on the incidence/prevalence of infection, nor is there a national control programme.
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影响因子：
7.7
作者：
Lopez-Caballero, J.;Oceguera-Figueroa, A.;Leon-Regagnon, V.
通讯作者：
Leon-Regagnon, V.
影响因子：
2.8
作者：
GUEVARA, A;VIEIRA, JC;CARLIER, Y
通讯作者：
CARLIER, Y
影响因子：
1.6
作者：
Iwagami, M;Monroy, C;Agatsuma, T
通讯作者：
Agatsuma, T
影响因子：
2.4
作者：
Blair, D;Agatsuma, T;Ito, A
通讯作者：
Ito, A
DOI：
10.1016/s0035-9203(98)90919-1
发表时间：
1998-09-01
影响因子：
2.2
作者：
Calvopiña, M;Guderian, RH;Cooper, PJ
通讯作者：
Cooper, PJ