Lifetime occupational history and risk of endometriosis.

Lifetime occupational history and risk of endometriosis.
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DOI:
10.5271/sjweh.1317
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发表时间:
2009-05
期刊:
Scandinavian journal of work, environment & health
影响因子:
--
通讯作者:
Davis S
Davis S
中科院分区:
其他
文献类型:
--
作者:
Marino JL;Holt VL;Chen C;Davis S

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子宫内膜异位症是指子宫腔外存在功能正常的子宫内膜腺体和间质,最常见于盆腔腹膜腔。患有子宫内膜异位症的女性通常有痛经、性交困难、疼痛、月经过多和/或子宫出血;疾病并发症包括粘连、慢性疼痛和不孕。本探索性病例对照研究以人群为基础,调查了终生职业史与手术确诊子宫内膜异位症之间的关系。访谈对象为1996年4月1日至2001年3月31日期间在一家大型保健机构首次诊断为手术确认子宫内膜异位症的所有育龄女性参保者,并从同一时期的育龄女性参保者名单中随机选择对照组。每个报告的工作都使用美国人口普查职业和行业代码进行编码,并将工作分类。使用无条件逻辑回归,将曾经在特定工作类别中工作过的职业与从未这样做过的职业进行比较。曾担任过空乘、服务站服务员或卫生工作者,特别是护士或卫生助理,与子宫内膜异位症的风险增加有关(空乘:or 9.80, 95% CI 1.08 - 89.02;服务站服务员:or 5.77, 95% CI 1.03 -32.43;卫生工作者:or 1.49, 95% CI 1.03 - 2.15)。收入和受教育程度对所调查职业的比值比估计没有影响。这项探索性研究表明,曾经担任过空姐、服务站服务员或卫生工作者,特别是护士,可能与子宫内膜异位症的风险增加有关。
Endometriosis is the presence of functioning endometrial glands and stroma outside the uterine cavity, most often in the pelvic peritoneal cavity. Women with endometriosis commonly have dysmenorrhea, dyspareunia, pain, menorrhagia and/or metrorrhagia; disease complications can include adhesions, chronic pain, and infertility. This exploratory case-control study investigated the relationship between lifetime occupational history and surgically confirmed endometriosis in a population-based sample. Interviews were conducted with cases, all reproductive-aged female enrollees of a large health-maintenance organization first diagnosed with surgically confirmed endometriosis between April 1, 1996 and March 31, 2001 and randomly selected controls from the reproductive-aged female enrollee list from the same time period. Each reported job was coded using US Census Occupations and Industries codes, and jobs were classed into categories. Having ever worked an occupation in a given job class was compared to never having done so using unconditional logistic regression. Having ever worked as a flight attendant, service station attendant, or health worker, particularly as a nurse or health aide, was associated with increased risk of endometriosis (flight attendant: OR 9.80, 95% CI 1.08 - 89.02; service station attendant: OR 5.77, 95% CI 1.03 -32.43; health worker: OR 1.49, 95% CI 1.03 - 2.15). Income and education did not make a difference in the odds ratio estimates for the occupations examined. This exploratory study suggests that having ever worked as a flight attendant, service station attendant, or health worker, particularly as a nurse, may be associated with an increased risk of endometriosis.
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发表时间: 2002-10-01
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