Metabolic syndrome and risk of cancer mortality in men.
Metabolic syndrome and risk of cancer mortality in men.
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DOI：
10.1016/j.ejca.2009.01.031
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发表时间：
2009-07
影响因子：
8.4
通讯作者：
Blair, Steven N.
中科院分区：
文献类型：
--
作者：
Jaggers, Jason R.;Sui, Xuemei;Hooker, P.;LaMonte, Michael J.;Matthews, Charles E.;Hand, Gregory A.;Blair, Steven N.
代谢综合征(METS)与罹患癌症的风险增加有关；然而，METS与癌症死亡率之间的联系尚不清楚。很少有研究关注可能影响治疗结果的癌前风险因素。这项研究的目的是研究蛋氨酸与男性全癌死亡率之间的关系。参与者包括33,230名年龄在20-88岁之间的男性，他们参加了有氧运动中心的纵向研究，在基线上没有已知的癌症。在基线时，所有参与者中有28%的人患有代谢综合征。在平均14年的随访中，共有685人死于癌症。甲硫氨酸水平与年龄调整后的癌症死亡率增加56%相关。这些数据表明，甲硫氨酸与男性全因癌症死亡率的增加有关。根据这些发现，显然应该确定成功的干预措施来减轻甲氨蝶呤的负面影响。
Metabolic syndrome (MetS) has been linked with an increased risk of developing cancer; however the association between MetS and cancer mortality remains less clear. Little research has focused on pre-cancer risk factors that may affect the outcome of treatment. The purpose of this study was to examine the association between MetS and all-cancer mortality in men. The participants included 33,230 men aged 20-88 years who were enrolled in the Aerobics Center Longitudinal Study and free of known cancer at baseline. At baseline 28% of all the participants had MetS. During an average of 14 years follow-up there were a total of 685 deaths due to cancer. MetS at baseline was associated with a 56% greater age-adjusted risk in cancer mortality. These data show that MetS is associated with an increased risk of all-cause cancer mortality in men. Based on these findings it is evident that successful interventions should be identified to attenuate the negative effects of MetS.
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影响因子：
8.8
作者：
Nilsen TI;Vatten LJ
通讯作者：
Vatten LJ
影响因子：
4.8
作者：
POLLOCK, ML;BOHANNON, RL;LINNERUD, AC
通讯作者：
LINNERUD, AC
影响因子：
120.7
作者：
Blair, SN;Kampert, JB;Gibbons, LW
通讯作者：
Gibbons, LW
影响因子：
--
作者：
Katzmarzyk, PT;Church, TS;Blair, SN
通讯作者：
Blair, SN
DOI：
10.1093/jnci/95.1.67
发表时间：
2003-01-01
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Hsing, AW;Gao, YT;Stanczyk, FZ
通讯作者：
Stanczyk, FZ