Chromosomal Aberrations in Cattle.

Chromosomal Aberrations in Cattle.
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DOI:
10.3390/genes12091330
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发表时间:
2021-08-27
期刊:
影响因子:
3.5
通讯作者:
Jutková A
Jutková A
中科院分区:
生物学3区
文献类型:
--
作者:
Holečková B;Schwarzbacherová V;Galdíková M;Koleničová S;Halušková J;Staničová J;Verebová V;Jutková A

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家畜染色体异常及其机制的研究已有多年。在牛身上,染色体异常通常与严重的生殖相关问题有关,如携带者不孕和胚胎早期死亡。在目前的工作中,我们回顾了最重要的牛染色体异常的机制和后果:罗伯逊易位和相互易位。我们还讨论了牛细胞培养在遗传毒性研究中的应用。
Chromosomal aberrations and their mechanisms have been studied for many years in livestock. In cattle, chromosomal abnormalities are often associated with serious reproduction-related problems, such as infertility of carriers and early mortality of embryos. In the present work, we review the mechanisms and consequences of the most important bovine chromosomal aberrations: Robertsonian translocations and reciprocal translocations. We also discuss the application of bovine cell cultures in genotoxicity studies.
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