The Tick Cell Biobank: A global resource for in vitro research on ticks, other arthropods and the pathogens they transmit.
The Tick Cell Biobank: A global resource for in vitro research on ticks, other arthropods and the pathogens they transmit.
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DOI：
10.1016/j.ttbdis.2018.05.015
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发表时间：
2018-07
影响因子：
3.2
通讯作者：
Makepeace BL
中科院分区：
文献类型：
--
作者：
Bell-Sakyi L;Darby A;Baylis M;Makepeace BL
壁虱细胞系越来越多地被用于壁虱和壁虱传播疾病的研究领域。扁虱细胞生物库成立于2009年，旨在促进这些独特而宝贵的资源的开发和利用。除了作为现有的和新的硬蜱和盘蚤细胞系的储存库，Tick Cell Biobank还向世界各地的科学家提供细胞系和维护培训，并从尚未出现在收藏中的壁虱物种中产生新的培养。现在，作为利物浦大学感染与全球卫生研究所的一部分，扁虱细胞生物库开始了一个新阶段的活动，专门针对扁虱、其他节肢动物及其在欠发达、低收入和中等收入国家传播的疾病造成的问题进行研究。我们正在对来自热带硬蜱物种的选定细胞系进行基因分型和表型鉴定。我们继续扩大培养范围，目前有63个细胞系，分别来自18种硬蜱和沼虾，以及来自沙蝇Lutzomia Longipalpis和咬人的库蚊的各一株，并正积极与合作者合作，从其他蚊种、螨类、采采蝇和蜜蜂获得用于原代细胞培养的起始材料。扁虱细胞生物库的前哨将设在马来西亚、肯尼亚和巴西，以促进这些国家和邻国的科学家对细胞系的吸收和利用以及相关培训。因此，扁虱细胞生物库将继续支持全球生物学研究的许多领域，以及扁虱、其他节肢动物和媒介传播的病毒、细菌和原生动物病原体的控制。
Tick cell lines are increasingly used in many fields of tick and tick-borne disease research. The Tick Cell Biobank was established in 2009 to facilitate the development and uptake of these unique and valuable resources. As well as serving as a repository for existing and new ixodid and argasid tick cell lines, the Tick Cell Biobank supplies cell lines and training in their maintenance to scientists worldwide and generates novel cultures from tick species not already represented in the collection. Now part of the Institute of Infection and Global Health at the University of Liverpool, the Tick Cell Biobank has embarked on a new phase of activity particularly targeted at research on problems caused by ticks, other arthropods and the diseases they transmit in less-developed, lower- and middle-income countries. We are carrying out genotypic and phenotypic characterisation of selected cell lines derived from tropical tick species. We continue to expand the culture collection, currently comprising 63 cell lines derived from 18 ixodid and argasid tick species and one each from the sand fly Lutzomyia longipalpis and the biting midge Culicoides sonorensis, and are actively engaging with collaborators to obtain starting material for primary cell cultures from other midge species, mites, tsetse flies and bees. Outposts of the Tick Cell Biobank will be set up in Malaysia, Kenya and Brazil to facilitate uptake and exploitation of cell lines and associated training by scientists in these and neighbouring countries. Thus the Tick Cell Biobank will continue to underpin many areas of global research into biology and control of ticks, other arthropods and vector-borne viral, bacterial and protozoan pathogens.
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影响因子：
3.2
作者：
Antunes S;Merino O;Mosqueda J;Moreno-Cid JA;Bell-Sakyi L;Fragkoudis R;Weisheit S;Pérez de la Lastra JM;Alberdi P;Domingos A;de la Fuente J
通讯作者：
de la Fuente J
DOI：
10.1016/j.bbagen.2012.12.016
发表时间：
2013-03-01
影响因子：
3
作者：
de Abreu, Leonardo Araujo;Calixto, Christiano;Logullo, Carlos
通讯作者：
Logullo, Carlos
影响因子：
3.2
作者：
Bell-Sakyi L;Palomar AM;Kazimirova M
通讯作者：
Kazimirova M
影响因子：
5.7
作者：
Bell-Sakyi L;Attoui H
通讯作者：
Attoui H
影响因子：
3.2
作者：
Alberdi, M. Pilar;Dalby, Matthew J.;Bell-Sakyi, Lesley
通讯作者：
Bell-Sakyi, Lesley