Human Platelets and Influenza Virus: Internalization and Platelet Activation.
Human Platelets and Influenza Virus: Internalization and Platelet Activation.
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DOI:
10.1080/09537104.2021.1961710
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发表时间:
2022-02-17
期刊:
影响因子:
3.3
通讯作者:
Koupenova M
中科院分区:
文献类型:
--
作者:
Bote J;Corkrey HA;Koupenova M
Influenza infection has long been associated with prothrombotic outcomes in patients and platelets are the blood component predominantly responsible for thrombosis. In this review, we outline what is known about influenza interaction with human platelets, virion internalization and viral RNA sensing, and the consequent impact on platelet function. We further discuss activation of platelets by IgG-influenza complexes and touch upon mechanisms of environmental platelet activation that relate to prothrombotic outcomes in patients during infection.
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发表时间:
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