Redistribution of U-snRNPs during mitosis.
Redistribution of U-snRNPs during mitosis.
复制标题
有丝分裂期间 U-snRNP 的重新分布。
DOI:
10.1016/0014-4827(86)90560-4
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发表时间:
1986
影响因子:
3.7
通讯作者:
Smith,HC
中科院分区:
文献类型:
--
作者:
Spector,DL;Smith,HC
In this study we examined the distribution of U-snRNPs during mitosis using a monoclonal antibody which recognizes the 28 kD protein associated with U-snRNP particles. During interphase U-snRNPs are concentrated within discrete intranuclear protein clusters. The onset of mitosis is accompanied by a breakdown of these nuclear protein clusters and U-snRNPs are redistributed between the condensing chromosomes. During metaphase and anaphase, two populations of U-snRNPs can be identified: those associated with the chromosome surface and a ‘free’ form distributed throughout the cytoplasm. During telophase, the reformation of nuclear protein clusters appears to be associated with the chromosome surface and coincides with chromatin decondensation. These studies suggest that the interphase assembly of nuclear domains containing U-snRNPs is sensitive to the transcriptionally active or decondensed state of chromatin.
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影响因子:
39.2
作者:
D. Notman;N. Kurata;E. Tan
通讯作者:
E. Tan
DOI:
10.1016/s0021-9258(18)96746-3
发表时间:
1966
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
M. Muramatsu;J. L. Hodnett;H. Busch
通讯作者:
H. Busch
影响因子:
14.9
作者:
S. Razin;V. L. Mantieva;G. Georgiev
通讯作者:
G. Georgiev
DOI:
--
发表时间:
1971
期刊:
Biochimica et Biophysica Acta
影响因子:
--
作者:
A. Rein
通讯作者:
A. Rein
影响因子:
64.5
作者:
S. Razin;V. V. Chernokhvostov;Andrej V. Roodyn;I. B. Zbarsky;G. Georgiev
通讯作者:
G. Georgiev