Pediatric Asthma Attack and Home Paint Exposure.
Pediatric Asthma Attack and Home Paint Exposure.
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DOI：
10.3390/ijerph18084118
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发表时间：
2021-04-13
影响因子：
--
通讯作者：
Kumar N
中科院分区：
文献类型：
--
作者：
Saif NT;Janecki JM;Wanner A;Colin AA;Kumar N
Although asthma mortality has been declining for the past several decades, asthma morbidity is on the rise, largely due to deteriorating indoor air quality and comorbidities, such as allergies. Consumer products and building materials including paints emit volatile organic compounds (VOCs), such as propylene glycol (PG), which is shown to dehydrate respiratory tracts and can contributor to airway remodeling. We hypothesize that paint exposure increases the risk of asthma attacks among children because high levels of VOCs persist indoors for many weeks after painting. Children 1–15 years old visiting two of the University of Miami general pediatric clinics were screened for their history of asthma and paint exposure by interviewing their parents and/or guardians accompanying them to the clinic. They were also asked questions about asthma diagnosis, severity of asthma and allergies and their sociodemographics. The risk of asthma attack among asthmatic children was modeled with respect to paint exposure adjusting for potential confounders using multivariate logistic regressions. Of 163 children, 36 (22%) reported physician-diagnosed asthma and of these, 13 (33%) had an asthma attack during the last one year. Paint exposure was marginally significant in the univariate analysis (OR = 4.04; 95% CI = 0.90–18.87; p < 0.1). However, exposed asthmatic children were 10 times more likely to experience an asthma attack than unexposed asthmatic children (OR = 10.49; CI = 1.16–94.85, p < 0.05) when adjusted for other risk factors. Given paint is one of the sources of indoor VOCs, multiple strategies are warranted to manage the health effects of VOC exposure from paint, including the use of zero-VOC water-based paint, exposure avoidance and clinical interventions.
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DOI：
10.1056/nejmra0910061
发表时间：
2010-12-02
期刊：
The New England journal of medicine
影响因子：
--
作者：
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通讯作者：
Dickey BF
影响因子：
--
作者：
Win-Shwe TT;Fujimaki H;Arashidani K;Kunugita N
通讯作者：
Kunugita N
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影响因子：
8.8
作者：
Deng, Qihong;Lu, Chan;Yuan, Hong
通讯作者：
Yuan, Hong
影响因子：
2.6
作者：
Guibas GV;Mathioudakis AG;Tsoumani M;Tsabouri S
通讯作者：
Tsabouri S
DOI：
10.3904/kjim.2014.29.2.183
发表时间：
2014-03
期刊：
The Korean journal of internal medicine
影响因子：
--
作者：
Hwang SS;Kang S;Lee JY;Lee JS;Kim HJ;Han SK;Yim JJ
通讯作者：
Yim JJ