From molecule to mind: an integrative perspective on odor intensity.

From molecule to mind: an integrative perspective on odor intensity.
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DOI:
10.1016/j.tins.2014.05.005
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发表时间:
2014-08
影响因子:
15.9
通讯作者:
Lowe G
Lowe G
中科院分区:
医学1区
文献类型:
--
作者:
Mainland JD;Lundström JN;Reisert J;Lowe G

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系统神经科学的一个基本问题是将刺激的物理特性映射到感知特征。在视觉中,波长转化为颜色;在试听中,频率转化为音高。虽然气味浓度是嗅觉刺激的一个关键特征,但我们不知道浓度是如何被嗅觉系统转化为感知强度的。据报道,在不同处理水平上的各种神经反应随着气味浓度的变化而变化,这表明了特定的编码模型。然而,目前尚不清楚,如果有的话,这些现象中的哪一个是气味强度感知的基础。在这里,我们提供了当前的模型在不同阶段的嗅觉处理的概述,并确定了未来的研究前景。
A fundamental problem in systems neuroscience is mapping the physical properties of a stimulus to perceptual characteristics. In vision, wavelength translates into color; in audition, frequency translates into pitch. Although odorant concentration is a key feature of olfactory stimuli, we do not know how concentration is translated into perceived intensity by the olfactory system. A variety of neural responses at several levels of processing have been reported to vary with odorant concentration, suggesting specific coding models. However, it remains unclear which, if any, of these phenomena underlie the perception of odor intensity. Here we provide an overview of current models at different stages of olfactory processing, and identify promising avenues for future research.
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