Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow.
Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow.
复制标题
麻醉大鼠微球门脉高压模型的表征:肝流量的比较。
DOI:
10.1016/s0163-7258(01)00123-1
复制
发表时间:
2001
影响因子:
13.5
通讯作者:
J. Reichen
中科院分区:
文献类型:
--
作者:
M. Van de Casteele;H. Sägesser;H. Zimmermann;J. Reichen
Several portal hypertensive animal models are available and frequently used for haemodynamic studies. The portal venous inflows, measured with microspheres in pentobarbital anaesthetised rats, are compared here. The partial portal vein ligation model is characterised by a high portal venous inflow, together with extensive portal systemic shunting, at the cost of portal sinusoidal flow. In carbon tetrachloride-induced micronodular cirrhosis, portal sinusoidal flow, which reaches liver parenchyma, is high, and this is more pronounced in the presence of ascites. In bile duct ligation and excision-induced cirrhosis, an increase in liver weight was not equally followed by an increase in portal sinusoidal flow, pointing to a relatively underperfused liver.
DOI:
10.1152/ajpheart.1983.245.6.h920
发表时间:
1983
期刊:
The American journal of physiology
影响因子:
--
作者:
Stanek,KA;Smith,TL;Murphy,WR;Coleman,TG
通讯作者:
Coleman,TG
DOI:
10.1152/ajpendo.1996.270.6.e1037
发表时间:
1996
期刊:
The American journal of physiology
影响因子:
--
作者:
Hawkins,PA;DeJoseph,MR;Hawkins,RA
通讯作者:
Hawkins,RA
DOI:
10.1152/ajpgi.1986.250.4.g535
发表时间:
1986
期刊:
The American journal of physiology
影响因子:
--
作者:
Benoit,JN;Womack,WA;Korthuis,RJ;Wilborn,WH;Granger,DN
通讯作者:
Granger,DN