Whole-brain steady-state CEST at 3 T using MR Multitasking.
Whole-brain steady-state CEST at 3 T using MR Multitasking.
复制标题
DOI：
10.1002/mrm.29109
复制
发表时间：
2022-05
影响因子：
3.3
通讯作者：
Li, Debiao
中科院分区：
文献类型：
--
作者：
Han, Pei;Cheema, Karandeep;Lee, Hsu-Lei;Zhou, Zhengwei;Cao, Tianle;Ma, Sen;Wang, Nan;Han, Hui;Christodoulou, Anthony G.;Li, Debiao
应用磁共振多任务快速三维稳态化学交换饱和转移(ss-CEST)成像。开发了一种采用重复ss-CEST模块的连续捕获序列。每个ss-CEST模块包含一个单瓣高斯饱和脉冲，然后是扰流梯度和八个闪光读数(一个“训练线”+七个“成像线”)。K空间采集采用三维笛卡尔编码。重建的CEST图像用四池洛伦兹拟合法进行量化。稳态CEST全脑覆盖，空间分辨率1.7×1.7×3.0mm3，每次饱和频率偏移5.6s。55种不同频率偏移量的总扫描时间为5.5分钟。来自多池拟合的定量CEST图显示，整个体积的图像质量一致。利用MR多任务处理技术，可在3T条件下在5.5min内完成全脑覆盖的3D稳态CEST。
To perform fast 3D steady-state chemical exchange saturation transfer (ss-CEST) imaging using MR Multitasking. A continuous acquisition sequence with repetitive ss-CEST modules was developed. Each ss-CEST module contains a single-lobe Gaussian saturation pulse, followed by a spoiler gradient and eight FLASH readouts (one “training line” + seven “imaging lines”). 3D Cartesian encoding was used for k-space acquisition. Reconstructed CEST images were quantified with four-pool Lorentzian fitting. Steady-state CEST with whole-brain coverage was performed in 5.6 sec per saturation frequency offset at the spatial resolution of 1.7 × 1.7 × 3.0 mm3. The total scan time was 5.5 min for 55 different frequency offsets. Quantitative CEST maps from multi-pool fitting showed consistent image quality across the volume. 3D steady-state CEST with whole-brain coverage can be done at 3T within 5.5 min using MR Multitasking.
登录
查看更多内容
影响因子：
3.3
作者：
Heo HY;Zhang Y;Jiang S;Lee DH;Zhou J
通讯作者：
Zhou J
影响因子：
3.3
作者：
Jones, Craig K.;Polders, Daniel;Hua, Jun;Zhu, He;Hoogduin, Hans J.;Zhou, Jinyuan;Luijten, Peter;van Zijl, Peter C. M.
通讯作者：
van Zijl, Peter C. M.
影响因子：
3.3
作者：
Lam, Fan;Liang, Zhi-Pei
通讯作者：
Liang, Zhi-Pei
影响因子：
28.1
作者：
Christodoulou AG;Shaw JL;Nguyen C;Yang Q;Xie Y;Wang N;Li D
通讯作者：
Li D
影响因子：
3.3
作者：
Chen L;Cao S;Koehler RC;van Zijl PCM;Xu J
通讯作者：
Xu J