Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells.

Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells.
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循环肿瘤细胞的生物学,检测技术和临床应用的进展。

DOI:
10.1155/2022/7149686
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发表时间:
2022
影响因子:
--
通讯作者:
--
中科院分区:
医学3区
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--
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循环肿瘤细胞(CTC)在肿瘤复发和转移中发挥着至关重要的作用,其早期检测在临床治疗诊断中显示出显着的益处。然而,CTC 极其罕见,因此在血液中检测它们非常具有挑战性。新的 CTC 检测技术正在不断开发,从而能够更深入地分析 CTC 生物学和潜在的临床应用。本文综述了当前CTC检测技术及其临床应用。 CTC 已经并将继续提供对转移过程的重要见解,这可能会导致针对不同癌症的新疗法的开发。
Circulating tumor cells (CTCs) play a crucial role in tumor recurrence and metastasis, and their early detection has shown remarkable benefits in clinical theranostics. However, CTCs are extremely rare, thus detecting them in the blood is very challenging. New CTC detection techniques are continuously being developed, enabling deeper analysis of CTC biology and potential clinical application. This article reviews current CTC detection techniques and their clinical application. CTCs have provided, and will continue to provide, important insights into the process of metastasis, which could lead to development of new therapies for different cancers.
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