Epidemiology and genetic characteristics of murine kobuvirus from faecal samples of Rattus losea, Rattus tanezumi and Rattus norvegicus in southern China.
Epidemiology and genetic characteristics of murine kobuvirus from faecal samples of Rattus losea, Rattus tanezumi and Rattus norvegicus in southern China.
复制标题
中国南方黄毛鼠、黄胸鼠和褐家鼠粪便中鼠科布病毒的流行病学和遗传特征
DOI：
10.1099/jgv.0.001646
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发表时间：
2021-09
期刊：
影响因子：
--
通讯作者：
Chen Q
中科院分区：
文献类型：
--
作者：
Zhang M;You F;Wu F;He H;Li Q;Chen Q
鼠科布病毒（murine kobuvirus，MuKV）是近年来在我国褐家鼠粪便中发现的一种小核糖核酸病毒。关于MuKV在其他鼠类物种中传播的有限信息促使我们调查其流行情况，并在中国黄毛鼠、黄胸鼠和褐家鼠中进行MuKV的遗传表征。2015年至2017年间，对来自中国南方三个地区的这三种啮齿动物物种的243份粪便样本进行了MuKV筛查。总患病率为23.0%（56/243）。获得了三个完整的MuKV多蛋白序列，并确定了基因组结构。系统发育分析表明，我们的序列与中国株关系密切，属于科布病毒属中的艾奇病毒A。需要进一步研究以了解MuKV在中国啮齿类鼠种群中的真实流行率。
Recently, murine kobuvirus (MuKV), a novel member of the family Picornaviridae, was identified in faecal samples of Rattus norvegicus in China. The limited information on the circulation of MuKV in other murine rodent species prompted us to investigate its prevalence and conduct a genetic characterization of MuKV in Rattus losea, Rattus tanezumi and Rattus norvegicus in China. Between 2015 and 2017, 243 faecal samples of these three murine rodent species from three regions in southern China were screened for the presence of MuKV. The overall prevalence was 23.0% (56/243). Three complete MuKV polyprotein sequences were acquired, and the genome organization was determined. Phylogenetic analyses suggested that our sequences were closely related to Chinese strains and belong to the species Aichivirus A in the genus Kobuvirus. Additional studies are required to understand the true prevalence of MuKV in murine rodent populations in China.
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影响因子：
3.2
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