Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: analysis of longitudinal data from the Osteoarthritis Initiative.
Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: analysis of longitudinal data from the Osteoarthritis Initiative.
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DOI：
10.1002/acr.20148
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发表时间：
2010-07
影响因子：
4.7
通讯作者：
Hunter, David J.
中科院分区：
文献类型：
--
作者：
Duryea, Jeffrey;Neumann, Gesa;Niu, Jingbo;Totterman, Saara;Tamez, Jose;Dabrowski, Christine;Le Graverand, Marie-Pierre Hellio;Luchi, Monica;Beals, Chan R.;Hunter, David J.
磁共振成像（MRI）和X线摄影是评估膝关节骨关节炎（OA）的既定成像方式。本研究的目的是比较骨关节炎倡议（OAI）参与者中放射学关节间隙宽度（JSW）与MRI衍生的软骨形态测量的反应性。本研究检查了来自OAI的150例受试者子集的基线和12个月访视。通过使用自动软件勾画关节的股骨和胫骨边缘，促进了影像学JSW的测量。内侧间室最小JSW和JSW在固定位置的措施进行了比较，来自MRI的软骨形态测量。结果按Kellgren和Lawrence（KL）分级和胫股解剖角分层。为了检查各种技术的相对反应性，我们计算了两次访视之间的标准化反应平均值（SRM）。在最佳位置测量的X射线JSW的SRM值为-0.32，而最敏感的MRI测量值为-0.39。对于KL = 2或3的亚组，放射学JSW和MRI的最敏感SRM值分别为-0.34和-0.42。我们的研究表明，在检测OA进展方面，使用数字化膝关节X线摄影图像软件分析的新措施与MRI相当，并且在考虑两种成像方式的成本效益时可能具有上级优势。
Magnetic resonance imaging (MRI) and radiography are established imaging modalities for the assessment of knee osteoarthritis (OA). The objective of our study is to compare the responsiveness of radiographic joint space width (JSW) to MRI derived measures of cartilage morphometry for OA progression in participants from the Osteoarthritis Initiative (OAI). This study examined the baseline and 12 month visits of a subset of 150 subjects from the OAI. Measurement of radiographic JSW was facilitated by the use of automated software that delineated the femoral and tibial margins of the joint. Measures of medial compartment minimum JSW and JSW at fixed locations were compared to cartilage morphometry measures derived from MRI. The results were stratified by Kellgren and Lawrence (KL) grade and by tibio-femoral anatomical angle. In order to examine the relative responsiveness of various techniques, we calculated the standardized response mean (SRM) between the two visits. The SRM value for radiographic JSW measured at the optimal location was −0.32 compared to −0.39 for the most responsive MRI measure. For a subgroup with KL = 2 or 3, the most responsive SRM values were −0.34 for radiographic JSW and −0.42 MRI. Our study demonstrates that new measures using a software analysis of digital knee radiographic images are comparable to MRI in detecting OA progression, and potentially superior when considering the cost effectiveness of the two imaging modalities.
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影响因子：
7
作者：
Duryea, J.;Neumann, G.;Lang, P.
通讯作者：
Lang, P.
影响因子：
27.4
作者：
Hunter, D. J.;Niu, J.;Beals, C. R.
通讯作者：
Beals, C. R.
影响因子：
19.7
作者：
PETERFY, CG;VANDIJKE, CF;GENANT, HK
通讯作者：
GENANT, HK
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作者：
Kraus, VB;Vail, TP;McDaniel, G
通讯作者：
McDaniel, G
影响因子：
27.4
作者：
Le Graverand, M-P Hellio;Vignon, E. P.;Wyman, B.
通讯作者：
Wyman, B.