Fragmented mitochondrial genomes of the rat lice, Polyplax asiatica and Polyplax spinulosa: intra-genus variation in fragmentation pattern and a possible link between the extent of fragmentation and the length of life cycle.
Fragmented mitochondrial genomes of the rat lice, Polyplax asiatica and Polyplax spinulosa: intra-genus variation in fragmentation pattern and a possible link between the extent of fragmentation and the length of life cycle.
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DOI：
10.1186/1471-2164-15-44
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发表时间：
2014-01-18
期刊：
影响因子：
4.4
通讯作者：
Shao R
中科院分区：
文献类型：
--
作者：
Dong WG;Song S;Jin DC;Guo XG;Shao R
吸血虱（Anoplura亚目）寄生在真兽目哺乳动物身上，在啮齿动物身上发现的540种吸血虱中有67%。感染人类和猪的五种吸血虱都有片段化的线粒体基因组，并且在片段化程度上有很大差异。为了了解是否有任何生活史因素与这种变异有关，我们分别对从大袋狸鼠（Bandicota indica）和亚洲家鼠（Rattus tanezumi）中收集的亚洲多板鼠（Polyplax asiatica）和棘多板鼠（Polyplax spinulosa）的mt基因组进行了测序。我们确定了所有的37个线粒体基因共同的动物在Polyplax asiatica和Polyplax spinulosa。这两种鼠虱的线粒体基因位于11个环形微型染色体上;每个微型染色体长2-4 kb，有2-7个基因。这两种鼠虱的蛋白质编码基因和核糖体RNA基因在微型染色体上的分布模式相同，但22个转运RNA基因中有8个的分布模式不同。Polyplax大鼠虱子的线粒体基因组平均在每个微型染色体上有3.4个基因，因此比人类虱子的线粒体基因组片段化程度低（每个微型染色体有2.1和2.4个基因），但比猪虱子的线粒体基因组片段化程度高（每个微型染色体有4.1个基因）。我们的研究结果揭示了不同的模式内的属Polyplax线粒体基因组片段化，并进一步表明，线粒体基因组片段化的程度和吸血虱的生命周期的长度之间可能存在反向联系。
Blood-sucking lice (suborder Anoplura) parasitize eutherian mammals with 67% of the 540 described species found on rodents. The five species of blood-sucking lice that infest humans and pigs have fragmented mitochondrial genomes and differ substantially in the extent of fragmentation. To understand whether, or not, any life-history factors are linked to such variation, we sequenced the mt genomes of Polyplax asiatica and Polyplax spinulosa, collected from the greater bandicoot rat, Bandicota indica, and the Asian house rat, Rattus tanezumi, respectively. We identified all of the 37 mitochondrial genes common to animals in Polyplax asiatica and Polyplax spinulosa. The mitochondrial genes of these two rat lice are on 11 circular minichromosomes; each minichromosome is 2–4 kb long and has 2–7 genes. The two rat lice share the same pattern for the distribution of the protein-coding genes and ribosomal RNA genes over the minichromosomes, but differ in the pattern for the distribution of 8 of the 22 transfer RNA genes. The mitochondrial genomes of the Polyplax rat lice have 3.4 genes, on average, on each minichromosome and, thus, are less fragmented than those of the human lice (2.1 and 2.4 genes per minichromosome), but are more fragmented than those of the pig lice (4.1 genes per minichromosome). Our results revealed distinct patterns of mitochondrial genome fragmentation within the genus Polyplax and, furthermore, indicated a possible inverse link between the extent of mitochondrial genome fragmentation and the length of life cycle of the blood-sucking lice.
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影响因子：
3.4
作者：
Light JE;Smith VS;Allen JM;Durden LA;Reed DL
通讯作者：
Reed DL
影响因子：
30.8
作者：
GISH, W;STATES, DJ
通讯作者：
STATES, DJ
DOI：
10.1016/b978-012074903-4/50016-9
发表时间：
2006-01-01
期刊：
LABORATORY RAT, 2ND EDITION
影响因子：
--
作者：
Baker, David G.
通讯作者：
Baker, David G.
影响因子：
5.8
作者：
Laslett, Dean;Canback, Bjorn
通讯作者：
Canback, Bjorn
影响因子：
5.8
作者：
Larkin, M. A.;Blackshields, G.;Higgins, D. G.
通讯作者：
Higgins, D. G.