Cryoablation and immunity in non-small cell lung cancer: a new era of cryo-immunotherapy.

Cryoablation and immunity in non-small cell lung cancer: a new era of cryo-immunotherapy.
复制标题

DOI:
10.3389/fimmu.2023.1203539
复制
发表时间:
2023
影响因子:
7.3
通讯作者:
--
中科院分区:
医学2区
文献类型:
--
作者:

文献摘要

参考文献

相似文献

尽管在过去十年中,肿瘤反应和患者生存率取得了显着进展,但肺癌的全身免疫治疗仅在约一半的治疗患者中产生了客观反应。鉴于这一局限性,目前正在研究综合战略,以提高答复率。冷冻消融已被提出作为一种这样的技术,以诱导免疫原性细胞死亡,并与系统性免疫疗法,包括免疫检查点抑制剂协同作用。冷冻消融传统上是在成像引导下进行的,尽管最近的技术进步允许支气管镜下进行。在此,我们回顾了冷冻消融在非小细胞肺癌中的临床前和临床证据,以及潜在的抗肿瘤免疫诱导。我们强调正在进行的研究,涉及这种方法,并提出未来的调查领域。
Despite remarkable advances in tumor response and patient survival in the past decade, systemic immunotherapies for lung cancer result in an objective response in only around half of patients treated. On the basis of this limitation, combination strategies are being investigated to improve response rates. Cryoablation has been proposed as one such technique to induce immunogenic cell death and synergize with systemic immunotherapies, including immune checkpoint inhibitors. Cryoablation has been traditionally delivered percutaneously with imaging guidance although recent technological advances allow for bronchoscopic delivery. Herein, we review the pre-clinical and clinical evidence for the use of cryoablation in non-small cell lung cancer and potential induction of anti-tumor immunity. We highlight ongoing studies involving this approach and propose areas of future investigation.
DOI: 10.1007/s00270-010-9868-0
发表时间: 2010-12-01
影响因子: 2.9
作者:
Hinshaw, J. Louis;Littrup, Peter J.;Brace, Christopher L.
通讯作者: Brace, Christopher L.
DOI: 10.1016/j.jtcvs.2005.12.051
发表时间: 2006-05-01
影响因子: 6
作者:
Kawamura, M;Izumi, Y;Kobayashi, K
通讯作者: Kobayashi, K
DOI: 10.1177/153303460400300202
发表时间: 2004-04-01
影响因子: 2.8
作者:
Baust, JG;Gage, AA
通讯作者: Gage, AA
DOI: 10.1016/j.jvir.2009.12.403
发表时间: 2010-08
期刊: Journal of vascular and interventional radiology : JVIR
影响因子: --
作者:
Erinjeri JP;Clark TW
通讯作者: Clark TW
DOI: 10.4103/atm.atm_392_17
发表时间: 2018-10
影响因子: 2.3
作者:
Jiang B;Mcclure MA;Chen T;Chen S
通讯作者: Chen S