Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: a systematic review with meta-analysis.
Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: a systematic review with meta-analysis.
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DOI：
10.1186/1479-5868-11-2
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发表时间：
2014-01-15
期刊：
影响因子：
--
通讯作者：
Callister R
中科院分区：
文献类型：
--
作者：
Aguiar EJ;Morgan PJ;Collins CE;Plotnikoff RC;Callister R
目前预防2型糖尿病的建议是改变饮食和运动习惯，包括有氧和抗阻训练。然而，涉及这三种成分组合的多成分干预的功效尚未确定。本综述的目的是系统回顾和荟萃分析多组分（饮食+有氧运动+阻力训练）生活方式干预预防2型糖尿病的证据。检索截至2013年6月的8个电子数据库（Medline、Embase、SportDiscus、Web of Science、CINAHL、Informit health collection、Cochrane library和Scopus）。1)招募糖尿病前期成人或有2型糖尿病风险的个体；2)进行饮食和运动[包括体力活动/有氧和阻力训练]计划；3)报告体重和血糖结果。共纳入8项研究的23篇文章，包括5项随机对照试验、1项准实验、1项两组比较和1项单组前后研究。4项研究的偏倚风险较低（评分≥6/10）。中位干预时间为12个月（范围4-48个月），随访18个月（范围6.5 - 48个月）。饮食和运动干预在具体处方方面略有不同。meta分析表明，干预措施在减重（-3.79 kg [-6.13, -1.46; 95% CI], Z = 3.19, P = 0.001）和空腹血糖（-0.13 mmol）方面优于对照组。L-1 [-0.24, -0.02；95% ci], z = 2.42, p = 0.02)。只有两项研究报告了糖尿病的发病率，与对照组相比分别降低了58%和56%。总之，多组分生活方式预防2型糖尿病的干预措施，包括饮食和有氧和阻力运动训练，在诱导体重减轻和改善空腹血糖受损、葡萄糖耐量、饮食和运动结果方面对高危和糖尿病前期成人人群有一定的效果。这些结果支持当前的运动指南，将阻力训练纳入2型糖尿病预防，但仍需要更严格的研究，长期随访评估项目效果、肌肉健康结果、糖尿病发病率和风险降低。
Current recommendations for the prevention of type 2 diabetes advise modification of diet and exercise behaviors including both aerobic and resistance training. However, the efficacy of multi-component interventions involving a combination of these three components has not been established. The aims of this review were to systematically review and meta-analyze the evidence on multi-component (diet + aerobic exercise + resistance training) lifestyle interventions for type 2 diabetes prevention. Eight electronic databases (Medline, Embase, SportDiscus, Web of Science, CINAHL, Informit health collection, Cochrane library and Scopus) were searched up to June 2013. Eligible studies 1) recruited prediabetic adults or individuals at risk of type 2 diabetes; 2) conducted diet and exercise [including both physical activity/aerobic and resistance training] programs; and 3) reported weight and plasma glucose outcomes. In total, 23 articles from eight studies were eligible including five randomized controlled trials, one quasi-experimental, one two-group comparison and one single-group pre-post study. Four studies had a low risk of bias (score ≥ 6/10). Median intervention length was 12 months (range 4–48 months) with a follow-up of 18 months (range 6.5 - 48 months). The diet and exercise interventions varied slightly in terms of their specific prescriptions. Meta-analysis favored interventions over controls for weight loss (-3.79 kg [-6.13, -1.46; 95% CI], Z = 3.19, P = 0.001) and fasting plasma glucose (-0.13 mmol.L-1 [-0.24, -0.02; 95% CI], Z = 2.42, P = 0.02). Diabetes incidence was only reported in two studies, with reductions of 58% and 56% versus control groups. In summary, multi-component lifestyle type 2 diabetes prevention interventions that include diet and both aerobic and resistance exercise training are modestly effective in inducing weight loss and improving impaired fasting glucose, glucose tolerance, dietary and exercise outcomes in at risk and prediabetic adult populations. These results support the current exercise guidelines for the inclusion of resistance training in type 2 diabetes prevention, however there remains a need for more rigorous studies, with long-term follow-up evaluating program efficacy, muscular fitness outcomes, diabetes incidence and risk reduction.
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影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
影响因子：
16.2
作者：
Dunstan, DW;Daly, RM;Zimmet, P
通讯作者：
Zimmet, P
影响因子：
2.5
作者：
Baldi, JC;Snowling, N
通讯作者：
Snowling, N
影响因子：
5.1
作者：
Dunstan, DW;Puddey, IB;Stanton, KG
通讯作者：
Stanton, KG
影响因子：
8.2
作者：
Corpeleijn, E.;Feskens, E. J. M.;Blaak, E. E.
通讯作者：
Blaak, E. E.