Antiprotozoal activity of medicinal plants against Ichthyophthirius multifiliis in goldfish (Carassius auratus)
Antiprotozoal activity of medicinal plants against Ichthyophthirius multifiliis in goldfish (Carassius auratus)
复制标题
药用植物对金鱼（Carassius auratus）多子鱼霉的抗原虫活性
DOI：
10.1007/s00436-012-3022-7
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发表时间：
2012-08
影响因子：
2
通讯作者：
Wang Gaoxue
中科院分区：
文献类型：
--
作者：
Lu Cheng;Hu Xuegang;Ling Fei;Wang Gaoxue
小瓜虫病是水产养殖中的一种普遍疾病，导致鱼类大量死亡。开发新的抗原生动物剂用于治疗多丝小瓜虫感染越来越引起人们的兴趣。研究了30种常用药用植物对稻瘟病菌的防治效果。多丝的结果表明，厚朴和苦豆子的甲醇提取物对疟原虫的活性最高，其4 h LC（50）值分别为2.45和3.43mg·L（-1）。浓度为2.5、5.0、10.0和20.0 mg L（-1）的M。在20 h时，药用植物提取物分别导致9.7%、43.7%、91.3%和100%的毛滴虫死亡率。40 ~ 320 mg L（-1）的S.苦豆子提取物使毛滴虫死亡率从29.7%提高到100%。还应用了对定居绒毛（2和10 h）的抗原虫效力;结果表明，成囊I。multifiliistomont对这些植物提取物处理不太敏感。体内实验表明，高浓度的M. officinalis和S.苦豆子提取物对小鼠有致死作用;结果表明，中药显著降低其繁殖率（P < 0.05）。这些结果表明，M. officinalis和S.苦豆子素具有作为一种生态友好的防治方法的潜力。多丝的
Ichthyophthiriasis is a widespread disease in aquaculture and causes mass mortalities of fish. The development of new antiprotozoal agents for the treatment of Ichthyophthirius multifiliis infections is of increasing interest. The aim of the present study was to investigate the efficacy of 30 medicinal plants against I. multifiliis. The results showed that the methanol extracts of Magnolia officinalis and Sophora alopecuroides displayed the highest antiprotozoal activity against theronts, with 4-h LC(50) values estimated to be 2.45 and 3.43 mg L(-1), respectively. Concentrations of 2.5, 5.0, 10.0, and 20.0 mg L(-1) of M. officinalis extracts resulted in tomont mortality of 9.7, 43.7, 91.3, and 100% at 20 h, respectively. From 40 to 320 mg L(-1) of S. alopecuroides extracts, tomont mortality increased from 29.7 to 100%. Antiprotozoal efficacy against settled tomonts (2 and 10 h) was also applied; the results indicated that encysted I. multifiliis tomonts were less susceptible to these plant extract treatments. In vivo experiments demonstrated that high concentrations of M. officinalis and S. alopecuroides extracts could kill tomonts, and M. officinalis significantly reduced its reproduction (P < 0.05). These results suggested that the methanol extracts of M. officinalis and S. alopecuroides have the potential to be used as an eco-friendly approach for the control of I. multifiliis.
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影响因子：
2
作者：
Wu, Zong-Fan;Zhu, Bin;Wang, Gao-Xue
通讯作者：
Wang, Gao-Xue
DOI：
10.2307/3284065
发表时间：
1995-12
期刊：
The Journal of parasitology
影响因子：
--
作者：
Jane G. Noe;Harry W. Dickerson
通讯作者：
Jane G. Noe;Harry W. Dickerson
影响因子：
2
作者：
Ekanem, AP;Obiekezie, A;Knopf, K
通讯作者：
Knopf, K
影响因子：
2.6
作者：
Yao, Jia-yun;Zhou, Zhi-ming;Shen, Jin-yu
通讯作者：
Shen, Jin-yu
DOI：
--
发表时间：
2011
期刊：
--
影响因子：
--
作者：
J. Abowei;O. F. Briyai;S. Bassey
通讯作者：
J. Abowei;O. F. Briyai;S. Bassey