Sleep-disordered breathing and atrial fibrillation.

Sleep-disordered breathing and atrial fibrillation.
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DOI:
10.1016/j.pcad.2008.06.004
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发表时间:
2009-03
影响因子:
9.1
通讯作者:
Somers, Virend K.
Somers, Virend K.
中科院分区:
医学2区
文献类型:
--
作者:
Caples, Sean M.;Somers, Virend K.

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心房颤动(AF)是美国最常见的持续性心律失常,患病率接近250万人,估计到2050年将有1000万人患病。1房颤研究表明,40岁的人一生中有1/4的风险发生房颤。2房颤的重要性源于其后遗症,特别是血栓栓塞性卒中和心力衰竭(HF),以及总体死亡率可能增加。3尽管药物和非药物治疗取得了进展,但房颤仍然是一个公共卫生问题,这激发了人们对替代治疗途径的兴趣,这些替代治疗途径可能来自对房颤继发性原因的更好管理,包括高血压、心肌病以及可能的睡眠呼吸障碍(基于越来越多的证据)。
Atrial fibrillation (AF) is the most common sustained arrhythmia in the United States, with a prevalence approaching 2.5 million persons and estimates of 10 million afflicted by the year 2050. 1 The Framingham Heart Study suggests that a forty year old has a 1 in 4 lifetime risk of developing AF. 2 The importance of AF stems from its sequelae, particularly thromboembolic stroke and heart failure (HF), and a possible increase in overall mortality. 3 Despite advances in drug and non-pharmacologic therapy, AF remains a public health problem, fueling interest in alternative avenues of treatment that may come from better management of secondary causes of AF which include hypertension, cardiomyopathy and possibly, based upon increasing evidence, sleep disordered breathing.
DOI: 10.1093/sleep/27.8.1507
发表时间: 2004-12-15
期刊: SLEEP
影响因子: 5.6
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