Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms.
Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms.
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DOI:
10.1016/j.conb.2014.10.012
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发表时间:
2015-04
影响因子:
5.7
通讯作者:
Otopalik AG
中科院分区:
文献类型:
--
作者:
Marder E;Goeritz ML;Otopalik AG
Small central pattern generating circuits found in invertebrates have significant advantages for the study of the circuit mechanisms that generate brain rhythms. Experimental and computational studies of small oscillatory circuits reveal that similar rhythms can arise from disparate mechanisms. Animal-to-animal variation in the properties of single neurons and synapses may underly robust circuit performance, and can be revealed by perturbations. Neuromodulation can produce altered circuit performance but also ensure reliable circuit function.
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